Neurorrhaphy Only vs Neurorrhaphy Plus PRF vs Neurorrhaphy Plus Nano-fat in Management of Traumatic Facial Nerve Injury

Condition(s) studied

Investigational drug(s) / intervention(s)

Platelets Rich Fibrin: Repair of facial nerve injury plus Platelets Rich Fibrin will be injected around the repair and measure the out come in comparison with (Repair only) and (Repair Plus Nano-fat stem cells)

Nano-fat stem cells (NFSCs): Repair of facial nerve injury plus Nano fat derived stem cells will be injected around the repair and measure the out come in comparison with (Repair only) and (Repair Plus Platelets Rich Fibrin).

Repair only: facial nerve neurorrhaphy only (repair only) after acute facial nerve trauma and measure the out come in comparison with (Repair plus Nano- fat Stem Cells) and (Repair Plus Platelets Rich Fibrin).

Study summary

The current clinical trial aims to identify the most significant intervention that improves the outcome of post-traumatic facial nerve injury by comparing the following different modalities: neurorrhaphy alone, neurorrhaphy with PRF injection, and neurorrhaphy with Nanofat stem cells graft injection for significantly better Facial nerve regeneration.

Eligibility

Primary outcome measure(s)

• Physical examination of the affected facial muscles after injury and Record the time taken for the first muscle excursion to occur following each facial nerve repair modality — 12 months
  \*\*Record the First Occurrence of Muscle Excursion and Movement by facial nerve Physical examination\*\* Based on monthly follow-up records Physical examination of the facial muscles affected after the nerve repair is done. Record the time taken for the first muscle excursion ( movement) to occur following each facial nerve repair modality. Comparing the time interval for each modality - the earlier the occurrence, the better the outcome.

Trial sites (1)

More Assiut University trials in Egypt

Other trials for the same condition