Role of Frozen Section in Categorization of Thyroid Follicular Neoplasm

Condition(s) studied

Investigational drug(s) / intervention(s)

Intraoperative Frozen Section: Intraoperative Frozen Section analysis which will include the following steps: \- The specimen will undergo both gross and microscopic examination: 1. Gross examination: Evaluation of nodular features including, multiplicity, size, outlines, color and consistency. 2. Microscopic examination: Assessment of capsular pattern, capsular invasion, thickness of capsule, vascular invasion and number of invaded vessels and the presence or absence of papillary structures.

Study summary

The goal of this prospective study is to assess the effectiveness of frozen section in distinguishing between benign and malignant tumors in the category of follicular thyroid neoplasm to prevent over-surgery for benign follicular neoplasm (lobectomy Vs total thyroidectomy).

The main questions, it aims to answer are:

The follicular neoplasm is benign or malignent? how far is FNAC valid and accurate? Researchers will compare the results of frozen section and paraffin embedded sections to evaluate the validity and accuracy of FNAC.

Eligibility

Primary outcome measure(s)

• Role of frozen section evaluation in the diagnosis of malignant follicular neoplasm from benign in Thyroid Follicular Neoplasm — two weeks
  Role of frozen section evaluation in the diagnosis of malignant follicular neoplasm from benign.

Trial sites (1)

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