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Clinical Trials in Egypt / NCT06896630
Starting soon Observational

Effect of Tenofovir (TDF) on Renal Function in Patients With Chronic Hepatitis B

NCT06896630 · tracked via the Priya Life Science Egypt tracker
Sponsor
Assiut University
Phase
Observational
Started
2025-04-10
Last updated
2025-04-04

Condition(s) studied

Tenofovir Disoproxil FumarateRenal Function DisorderChronic HBV Infection

Investigational drug(s) / intervention(s)

Tenofovir Disoproxil Fumarate (TDF) →

Tenofovir Disoproxil Fumarate (TDF): ANTIVIRAL TREATMENT FOR CHRONIC HEPATITIS B VIRUS INFECTION

Study summary

Effect of Long-Term Use of Tenofovir (TDF) on Renal Function in Patients with Chronic Hepatitis B Over a Five-Year Period

Eligibility

Sex
ALL
Min age
18 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria: Adult male or female patients aged 18 to 60 years. Diagnosed as HBV-positive. Long-term use of Tenofovir Disoproxil Fumarate (TDF) for more than five years. Exclusion Criteria: Presence of other chronic liver diseases. Diagnosed with Chronic Kidney Disease (CKD), regardless of etiology. Patients who refuse to participate in the study. Patients on combination therapy, including: Interferon and Nucleoside analogue combination therapy. Multiple nucleoside analogue combination therapy.

Primary outcome measure(s)

  • Changes in eGFR in Patients on Long-Term Tenofovir (TDF) Therapy — BASELINE
    "Renal function will be assessed using estimated glomerular filtration rate (eGFR) calculated by the CKD-EPI equation
  • Assessment of Renal Function: Serum Creatinine in Patients on Long-Term Tenofovir (TDF) Therapy — BASELINE
    "Renal function will be assessed using serum creatinine levels measured through standard laboratory assays.
  • proteinuria will be evaluated through urine protein-to-creatinine ratio — BASELINE
    proteinuria will be evaluated through urine protein-to-creatinine ratio (if applicable).

Trial sites (1)

FacilityCityRegionStatus
Faculty of Medicine Asyut Egypt

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Real-Time (TRUS) Guidance in Endoscopic Treatment of BPH Starting soon
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Other trials for the same condition

Effect of Long-Term Use of Tenofovir (TDF) on Bone Density in Patients With Chronic Hepatitis B Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06896630 on ClinicalTrials.gov ↗ ← All trials in Egypt