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Clinical Trials in Egypt / NCT06777381
Enrolling by invitation Not applicable

Comparison of Post-Operative Pain Occurrence After Single Visit Root Canal Treatment

NCT06777381 · tracked via the Priya Life Science Egypt tracker
Sponsor
National Research Centre, Egypt
Phase
Not applicable
Started
2024-10-25
Last updated
2025-01-15

Condition(s) studied

Symptomatic Irreversible Pulpitis

Investigational drug(s) / intervention(s)

single visit root canal treatment using ProTaper Universal rotary systemsingle visit root canal treatment using M-Pro rotary system

single visit root canal treatment using ProTaper Universal rotary system: single visit endodontic treatment will be performed using ProTaper Universal rotary system for root canal preparation.

single visit root canal treatment using M-Pro rotary system: single visit endodontic treatment will be performed using MPro rotary systems for root canal preparation.

Study summary

The goal of this clinical trial is to compare the post-operative pain occurrence after single visit root canal treatment using Two NiTi Rotary Files. The main question it aims to answer is:

• Does an instrument design and instrumentation technique could affect postoperative pain incidence and intensity? Researchers will use ProTaper Universal rotary system or M-Pro rotary system for root canal preparation and compared postoperative pain intensity.

Participants will receive single visit endodontic treatment using either ProTaper or MPro systems for root canal preparation.

Participants will record Pain intensity at 24 hours and 7 days post-operative. Analgesics will be prescribed for the patients in need.

Eligibility

Sex
ALL
Min age
25 Years
Max age
45 Years
Healthy volunteers
No
Inclusion Criteria: * Patient's diagnosis is symptomatic irreversible pulpitis in mandibular first molar. * Males and females patients in a good health. * Aged from 25 to 45 years old. * Pulp vitality is confirmed with cold pulp test and an electric pulp test. Exclusion Criteria: * Pregnant females. * Patients complaining from pain in more than one molar on the same side. * Patients whose teeth react positively to percussion test. * Patients who receive analgesics 12 hours before the start of the root canal treatment. * Teeth having grade 2 or 3 mobility. * Presence of periapical radiolucency or teeth with extra oral or intraoral sinus tract or fistula.

Primary outcome measure(s)

  • Record the intensity of postoperative pain after root canal treatment with ProTaper Universal and M-Pro endodontic rotary files. — 7 days
    Pain intensity will be recorded by the patient 24 hours and 7 days postoperatively. Pain assessment is evaluated using 10-point Numerical Rating Scale, where the endpoints are the extremes of no pain and worst pain. The severity of pain is assigned as follows: (0) equivalent to none/ (1) equivalent to slight pain / (2) equivalent to moderate pain and (3) equivalent to severe pain.

Trial sites (1)

FacilityCityRegionStatus
Dental Clinic at Medical Research Centre of Excellence, National Research Centre Cairo Egypt

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Other trials for the same condition

Vital Pulp Therapy Versus Root Canal Treatment for Irreversible Pulpitis With Incipient Apical Periodontitis Diagnosed Using Artificial Intelligence This Keeps: the Main Intervention (Vital Pulp Therapy) the Comparison (Root Canal Treatment) the Condition (Irreversible Pulpitis With Incipient Apic Active, not recruiting
The Effect of XP-Endo Finisher Activation of Bioceramic Sealer on Postoperative Pain in Mandibular First Molar With Symptomatic Irreversible Pulpitis Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06777381 on ClinicalTrials.gov ↗ ← All trials in Egypt