Doppler Echocardiography Versus Clinical Targets Guided Therapy on the Outcome of Postpartum Septic Shock.

Condition(s) studied

Investigational drug(s) / intervention(s)

a clinically guided resuscitation protocol,: a clinically guided resuscitation protocol, derived from EGDT and modified to match with the latest survival sepsis campaign guidelines

a transthoracic bedside focused echocardiographic assessment: a transthoracic bedside focused echocardiographic assessment of the patient will be done, as a baseline ECHO in a three-step approach to monitor hemodynamics using Logiq P7, S5-1 ECHO probe;

Study summary

Postpartum sepsis is widely known as a preventable main cause of maternal morbidity and mortality. According to the World Health Organization, approximately 11% of the estimated maternal deaths worldwide were attributed to sepsis. Recent global assessments indicate that obstetric infections rank as the third most prevalent cause of maternal death, with a prevalence mainly observed in low- and middle-income nations.

Eligibility

Primary outcome measure(s)

• SOFA score — 48 hours.
  The change in Sequential Organ Failure Assessment (SOFA score)

Trial sites (1)

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