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Recruiting Phase 1/2

Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy

NCT05821075 · tracked via the Priya Life Science Egypt tracker
Phase
Phase 1/2
Started
2023-08-24
Last updated
2025-07-31

Condition(s) studied

Bell Palsy

Investigational drug(s) / intervention(s)

Prednisolone →Cerebrolysin →

Prednisolone: prednisolone 60mg tablet once daily for 5 days then tapering dose

Cerebrolysin: intramuscular Cerebrolysin 10 mg daily for 3 weeks

Study summary

Bell's palsy, a peripheral facial nerve paresis, is the most common disorder of the facial nerve and one of the most common mononeuropathies.

Many patients with Bell's palsy will develop some complications such as synkinesis, crocodile tears and 'sweating' of the ear while eating Commonly used medications to treat Bell's palsy is Corticosteroids Cerebrolysin stimulates the regeneration of the nervous tissue with protective action we aim to study the efficacy of cerebrolycin in Bell's palsy

Eligibility

Sex
ALL
Min age
18 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria: * unilateral acute facial palsy of no identifiable cause Exclusion Criteria: * Recurrent facial Bell's palsy * Pregnancy * Diabetes * Epilepsy * Severe hypertension, * Renal or hepatic disease, * Gastric or duodenal ulcer * presence of acute otitis media or ipsilateral chronic otitis * Recent head injury, * psychiatric disease * If there is any contraindications for corticosteroids

Primary outcome measure(s)

  • change in scores of the house Brackman grading system HB — at baseline, after 1 week, after 3 week
  • changes in scores of the Sunnybrook grading system. — at baseline, after 1 week, after 3 week

Trial sites (1)

FacilityCityRegionStatus
October 6 university hospital Giza Egypt Recruiting

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05821075 on ClinicalTrials.gov ↗ ← All trials in Egypt