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Recruiting Observational

HFNC in Management of Bronchiectasis Exacerbation

NCT05741697 · tracked via the Priya Life Science Egypt tracker
Phase
Observational
Started
2023-03-01
Last updated
2026-09-24

Condition(s) studied

Bronchiectasis

Investigational drug(s) / intervention(s)

bi-level ventillation

bi-level ventillation: non-invasive mechanical ventilation

Study summary

Patients with Bronchiectasis experience exacerbations with hypercapnic respiratory failure associated with an increased respiratory workload that may require intensive care unit (ICU) admission due to the inability of the respiratory muscles to compensate for increased demand. These exacerbations are frequently treated with noninvasive ventilation (NIV).

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: * Patients will be eligible for enrolment if diagnosed with bronchiectasis and admitted to the respiratory intensive care unit (RICU), requiring ventilator support without invasive mechanical ventilation. Exclusion Criteria: * Age: less than 18 years. Patients with post-arrest encephalopathy. Patient with the previous tracheotomy. Patients who received invasive ventilatory support. Patients with end-organ failure.

Primary outcome measure(s)

  • Assessment of efficacy and patient compliance of high flow nasal canula system in comparison to Noninvasive mechanical ventilation in management of acute exacerbation of Bronchiectasis — March 2023 to December 2023
    The duration of ICU admission days and the patient compliance to both devices will be compared.

Trial sites (1)

FacilityCityRegionStatus
Assiut University-Faculty of medicine Asyut Egypt Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05741697 on ClinicalTrials.gov ↗ ← All trials in Egypt