Permissive Hyperthermia in Acute Brain Injury

Condition(s) studied

Investigational drug(s) / intervention(s)

Temperature < 39,5: Allowing temperature up to 39,5 in patients with acute brain injury

Temperature <37.5: Standard care of temperature

Study summary

The purpose of this pilot study is to find out whether it is possible to work together with the body's own reactions, where the temperature goes up (fever), in a safe and controlled way.

The main question to answer is:

Is it practical and safe to allow higher body temperature (up to 39.5°C) as part of the treatment for critically ill patients with brain injury?

Patients with acute brain injury will be Placed in one of two groups: one where fever is treated to keep the temperature below 37.5°C, and one where fever is allowed up to 39.5°C.

Eligibility

Primary outcome measure(s)

• Record numbers of episodes and the time frame when temperature needed to be lowered to maintain acceptable intracranial pressure. — 14 days from enrollment, or until multi-bolt has been removed, or the patients had died
  This only applies to patients included in the group, where temperatures up to 39.5°C are allowed

Trial sites (1)

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