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Recruiting Not applicable

Zinc Supplementation and Inflammation in Older Medical Patients

NCT07672132 · tracked via the Priya Life Science Denmark tracker
Phase
Not applicable
Started
2026-06-02
Last updated
2026-09-24

Condition(s) studied

Older Medical Patients

Investigational drug(s) / intervention(s)

Zinc Supplement

Zinc Supplement: 22 mg Zinc supplementation daily for 12 months

Study summary

The hypothesis is that a daily supplement of 22 mg of zinc over 12 months can reduce in-flammatory biomarkers in acutely hospitalized older adults aged ≥ 65 years.

The aims are to determine, in acutely hospitalized older adults aged ≥ 65 years, if a daily supplement of 22 mg of zinc over 12 months compared to control can decrease inflammato-ry biomarkers, reduce symptoms of self-reported infection, reduce readmission and mortali-ty, increase QoL, increase physical performance, investigate potential adverse events to zinc supplement, and the changes in inflammatory biomarkers. It will also be studied if albumin-corrected zinc in plasma is a more accurate method for assessing zinc status than ordinary plasma zinc.

Eligibility

Sex
ALL
Min age
65 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * above 65 years old included in ZOOM out ( clinical trials no: NCT07367412) * admittet at the medical emergency department Herlev Hospital Exclusion Criteria: * Patients receiving zinc supplements (\>10 mg daily) at time of inclusion * Patients with terminal illness (life expectancy \< 6 months, estimated by Clinical Frailty Scale ≥8) * Patients receiving parenteral nutrition (partial or complete) * Patients treated with hemodialysis or peritoneal dialysis * Patients known with severe dementia * Patients who do not understand Danish and patients with temporary civil person registration numbers (CPR)

Primary outcome measure(s)

  • inflammation 6 months — 6 months
    To evaluate the difference between the groups in plasma concentrations of IL-6 during the first 6-months. Endpoints: Plasma concentration of IL-6 (pg/ml) from baseline to 6 months

Trial sites (1)

FacilityCityRegionStatus
Herlev Hospital Herlev Region Hovedstad Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07672132 on ClinicalTrials.gov ↗ ← All trials in Denmark