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Clinical Trials in Denmark / NCT07384689
Recruiting Not applicable

Microenvironment in Patients Undergoing Non-traumatic Amputation

NCT07384689 · tracked via the Priya Life Science Denmark tracker
Sponsor
University of Aarhus
Phase
Not applicable
Started
2025-08-01
Last updated
2026-02-12

Condition(s) studied

Lower Limb Amputation Above Knee

Investigational drug(s) / intervention(s)

ciNPWTSSD

ciNPWT: Closed incision negative pressure wound therapy

SSD: Standard stump dressing

Study summary

The microenvironment of the amputation stump in patients undergoing non-traumatic transfemoral amputation will be investigated with a combination of microdialysis and tissue sampling.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion criteria * 18 years or older * Cognitive ability to provide informed consent * Scheduled for transfemoral amputation at Aarhus University Hospital Exclusion criteria * Non-vascular indication of amputation * Already amputated on the contralateral leg * Insufficient flap perfusion * Allergic or sensitivity to silver or acrylic adhesives

Primary outcome measure(s)

  • Ischemia — Within 72 hours postoperatively
    Concentration of ischemic metabolites: Glucose, Lactate, Pyruvate and Glycerol

Trial sites (1)

FacilityCityRegionStatus
Aarhus University Hospital Aarhus N Denmark Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07384689 on ClinicalTrials.gov ↗ ← All trials in Denmark