Fluorescence-Guided Optimization of Sarcoma Margins

Condition(s) studied

Investigational drug(s) / intervention(s)

Fluorescent-guided Surgery: Surgical treatment of the patient group will include the administration of a fluorescent dye and intraoperatively the resection will be aided and guided by the fluorescent signal. The wound bed will be inspected, areas with fluorescent signal will be excised and obtained separately for histopathology. Patients will receive the current post-operative standard of care for sarcoma patients

Study summary

This is a Danish national multicenter prospective cohort study to evaluate if fluorescence-guided surgery (FGS) using indocyanine green (ICG) can reduce the rate of positive margins following sarcoma resection.

Eligibility

Primary outcome measure(s)

• Reresection — 30 days
  Reresection within 30 days will be used as primary endpoint as a proxy for histopathologically positive margin status following surgery which would require reoperation.

Trial sites (2)

More University of Aarhus trials in Denmark

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