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Clinical Trials in Denmark / NCT07110324
Recruiting Observational

Characteristics of Persistent Pain Composition Following Total Hip or Knee Arthroplasty: a Descriptive Study

NCT07110324 · tracked via the Priya Life Science Denmark tracker
Sponsor
Copenhagen University Hospital, Rigshospitalet
Phase
Observational
Started
2025-06-26
Last updated
2026-04-01

Condition(s) studied

Pain (Visceral, Somatic, or Neuropathic)Hip Arthroplasty ReplacementKnee Arthroplasty, TotalSurvey and Questionnaire

Study summary

Despite high success rates of hip and knee arthroplasty, up to 20% of patients report moderate-to-severe pain (NRS \> 3) persisting beyond the expected healing period. This investigator-initiated, descriptive cohort study will re-invite approximately 100 consenting patients with persistent postoperative pain-identified from a pool of \~7 000 respondents-to complete standardized assessments of neuropathic (DN4), nociplastic (IASP criteria + Fibromyalgia Survey Questionnaire) and nociceptive (KOOS/HOOS pain domains) pain. Primary outcomes are the prevalence of potential nociplastic pain and the proportion experiencing significant pain in two or more mechanistic categories. Secondary analyses will compare baseline vs. re-evaluated DN4 scores, FSQ and KOOS/HOOS distributions, and examine differences between patients with and without possible neuropathic pain. Findings will inform targeted pre- and postoperative pain management strategies.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * All patients with persistent moderate-severe pain (NRS\>3) after THA, TKA and UKA * Acceptance to be contacted. Exclusion Criteria: * Re-operation * Luxation * Do not want to be contacted * Post-operative complications such as prosthesis infection, thromboembolism or fracture of the prosthesis.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Rigshospitalet Østerbro København Ø Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07110324 on ClinicalTrials.gov ↗ ← All trials in Denmark