Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact
Clinical Trials in Denmark / NCT06334172
Recruiting Not applicable

The Role of Oxytocin in Regulating Blood Glucose

NCT06334172 · tracked via the Priya Life Science Denmark tracker
Sponsor
University Hospital, Gentofte, Copenhagen
Phase
Not applicable
Started
2024-01-01
Last updated
2024-04-04

Condition(s) studied

Glucose Metabolism Disorders (Including Diabetes Mellitus)

Investigational drug(s) / intervention(s)

Oxytocin →Placebo

Oxytocin: Oxytocin

Placebo: Saline

Study summary

Investigating the effect of oxytocin on pancreatic endocrine functions by determining insulin and glucagon secretion within physiological ranges of plasma glucose.

Eligibility

Sex
MALE
Min age
20 Years
Max age
50 Years
Healthy volunteers
No
Inclusion Criteria: * BMI 19-25 kg/m2 Exclusion Criteria: * Diabetes * Heart-, liver or kidney disease * More than 14 units of alcohol weekly, or drug abuse * Smoking or any kind of nicotine products * Alanin aminotransferase (ALAT) ≥ 2 × normal range * Estimated glomerular filtration rate (eGFR) \< 60 ml/min/1,73m2 or creatinine above normal range * Blood pressure \> 140/90 * Hemoglobin \< normal range * Corrected QT Interval (Qtc) \>0,45 sec. at electrocardiogram (ECG) at screening * Known disease in the pituitary gland or previous pituitary surgery * Any other disease/condition which the trial managers believe may affect participation in the trial

Primary outcome measure(s)

  • Insulin secretion - c-peptide — From time 0 to time 180 min
    Insulin secretion, measured as percentual increase of area under the curve (AUC) for circulating c-peptide

Trial sites (1)

FacilityCityRegionStatus
Center for Clinical Metabolic Research, Gentofte Hospital Hellerup Capital Region Recruiting

More University Hospital, Gentofte, Copenhagen trials in Denmark

Effects of Antagonizing the Ghrelin Receptor on Brain Food Cue Reactivity in Obesity Active, not recruiting
Pancreatic Polypeptide as a Modulator of Amylin- Induced Satiety in Healthy Humans Recruiting
The Relationship Between Inflammatory ARTritis and CArdiac DIseAse Active, not recruiting
The Involvement of the Gut Hormone GIP in the Pathophysiology of Post Prandial Hypotension Enrolling by invitation
Medial Unicondylar Knee Arthroplasty vs Total Knee Arthroplasty Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06334172 on ClinicalTrials.gov ↗ ← All trials in Denmark