Physical Attendance Versus Telephone or Video Follow-up in Patients With Non-functioning Pituitary Tumors.

Condition(s) studied

Investigational drug(s) / intervention(s)

Telephone-/video follow-up: The yearly routine review of patients takes place by using a telephone or video interview rather than in-person interview in the endocrine outpatient department. All other assessments, e.g. biochemical, MRI, is conducted as usual.

In-person follow-up: The yearly routine review on patients takes place at the endocrine outpatient department

Study summary

The primary purpose of this study is to compare the safety of routine telephone assessment versus in-person assessment during a two-year period for patients with non-functioning pituitary adenomas. Secondly, to compare the quality of pituitary care in persons having biochemical assessment once versus twice a year. Thirdly, to assess the rationale of repeated assessment of pituitary function and imaging in patients with small pituitary tumors (microadenomas).

Eligibility

Primary outcome measure(s)

• Composite outcome of adverse events — Two year period. From allocation including the routine follow-up after two years.
  The primary outcome is a composite outcome comprised of the three individual outcomes considered of equal importance to patients and clinicians: Risk of admission for adrenal crisis, risk of admission for severe hypo- or hypernatremia, risk of pituitary surgery with lack of full recovery of vision after surgery.

Trial sites (1)

More Zealand University Hospital trials in Denmark