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Clinical Trials in Czechia / NCT07248527
Active, not recruiting Observational

PAN-ICIS Study: ICIS for Early Detection of Infectious Complications in Pancreatic Surgery

NCT07248527 · tracked via the Priya Life Science Czechia tracker
Sponsor
Charles University, Czech Republic
Phase
Observational
Started
2025-11-01
Last updated
2025-12-01

Condition(s) studied

PancreatectomyPancreatic SurgeryIntensive Care (ICU)Inflamatory MarkersPostoperative CarePostoperative Pancreatic FistulaSurgical Site Infection After Major SurgeryPostoperative Complications

Study summary

This study examines a new blood test called ICIS, which may help detect infections earlier after pancreatic surgery. Patients will have routine blood samples taken during their hospital stay, with no extra procedures required. By tracking how ICIS changes over time, investigators aim to improve early infection detection, support safer recovery, and reduce postoperative complications.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patients ≥ 18-years-old * Indication for an elective pancreatic procedure * Written informed consent Exclusion Criteria: * Patients \<18 years old. * Known hematologic malignancy or hematological pathology. * Refusal to participate.

Primary outcome measure(s)

  • Primary outcome — From day one after surgery to the end of hospitalization
    Diagnostic accuracy of ICIS for detecting postoperative infectious complications, measured by area under the receiver operating characteristic curve (AUROC), sensitivity, specificity, positive and negative predictive values, and likelihood ratios at prespecified cut-offs (e.g., ≥3, ≥4, ≥5).

Trial sites (1)

FacilityCityRegionStatus
Department of Surgery 2nd Faculty of Medicine, Charles University and Military University Hospital Prague Prague Prague 6

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Other trials for the same condition

The Effect of Perioperative Nutritional Care on Recovery After Knee and Hip Replacement Surgery Recruiting
Cardiopulmonary Exercise Testing in Cardiosurgery Patients Recruiting
Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures. Starting soon
Evaluate the Performance of the Dexcom G7 Continuous Glucose Monitoring (CGM) System in Critically Ill Patients Undergoing Major Abdominal Surgery and Solid Organ Transplantation Which Require Blood Glucose Monitoring for Intensive Insulin Therapy. Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07248527 on ClinicalTrials.gov ↗ ← All trials in Czechia