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Clinical Trials in Czechia / NCT07160153
Recruiting Observational

Cannabis Abstinence and Neurocognitive Assessment in Adolescence

NCT07160153 · tracked via the Priya Life Science Czechia tracker
Sponsor
University Hospital Pilsen
Phase
Observational
Started
2024-12-03
Last updated
2025-09-19

Condition(s) studied

Cannabis DependenceHarmful UseCognitive Assessment

Investigational drug(s) / intervention(s)

Neurocognitive assessmentUrine toxicological assessment

Neurocognitive assessment: Neurocognitive battery: TMT-Trail Making Test Auditory Verbal Learning Test Stroop Test Tower of London (ToL), Shallice version Continuous Performance Test-Identical Pairs Other psychometrics: The level of dependence is quantified using the CAST (Cannabis Abuse Screening Test)

Urine toxicological assessment: Urine toxicological assessment

Study summary

Cannabis Abstinence and Neurocognitive Assessment in Adolescence

Eligibility

Sex
ALL
Min age
15 Years
Max age
18 Years
Healthy volunteers
No
Inclusion Criteria: * Adolescents aged 15-18 years with a diagnosis of cannabis dependence or harmful cannabis use. Exclusion Criteria: * psychiatric comorbidity - Dual diagnosis, including psychotic disorders, mood disorders, severe organic brain damage, or autism spectrum disorder, with the exception of compensated and stabilized anxiety disorder. Psychopharmacological treatment is permitted, except for antipsychotics prescribed for psychosis. * somatic comorbidity - Severe endocrine disorders such as diabetes mellitus, thyroid dysfunction, or severe cardiovascular disease. * Violation of abstinence between the first and second neuropsychological assessments, as well as severe decompensation of mental state requiring modification of established psychopharmacological treatment.

Primary outcome measure(s)

  • Change in performance TMT-B — 8 weeks
    Change in performance on the Trail Making Test - Part B (TMT-B) \[Time Frame: after 8 weeks of abstinence from cannabis\]

Trial sites (1)

FacilityCityRegionStatus
University Hospital Pilsen Pilsen Czechia Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07160153 on ClinicalTrials.gov ↗ ← All trials in Czechia