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Trackers› Clinical trials› Canada
Clinical trial register · Canada

Studies with a Canadian investigative site

Every study on the ClinicalTrials.gov registry that lists a site in Canada and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage โ€” all 6540 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:55 UTC
6540
Studies in scope
all four open statuses
3515
Recruiting now
open to new participants
887
Lead sponsors
across recruiting studies
Top sites
Toronto 2809 Montreal 1902 Vancouver 1179 Calgary 1061 Edmonton 1017
Narrow the register
Recruitment status
Phase
Lead sponsor
University Health Network, Toronto349 University of British Columbia197 AstraZeneca190 University of Alberta180 University of Calgary149
Site location
Toronto2809 Montreal1902 Vancouver1179 Calgary1061 Edmonton1017
All 255 locations
Target enrolment
to

Trials in this register

6540 of 6540 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Canada
Start
Recruiting
Liquid Biopsy Evaluation and Repository Development at Princess Margaret
NCT03702309Cancer, Breast Cancer, Lung Cancer, Colon Cancer
University Health Network, Toronto
Observational
2,500
Toronto
2017-08-03
Active, closed
A Study of AT132 in Young Children With X-Linked Myotubular Myopathy (XLMTM)
NCT03199469X-Linked Myotubular Myopathy
Astellas Gene Therapies
Phase 2/3
27
Toronto
2017-08-02
Active, closed
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
NCT03155620Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Non-Hodgkin Lymphoma, Ann Arbor Stage IV Non-Hodgkin Lymphoma, Histiocytic Sarcoma
DrugsSamotolisib·Erdafitinib·Larotrectinib·Ensartinib
National Cancer Institute (NCI)
Phase 2
1,377
Montreal
2017-07-31
Recruiting
International Registry for Men With Advanced Prostate Cancer (IRONMAN)
NCT03151629Prostate Cancer
Prostate Cancer Clinical Trials Consortium
Observational
5,000
Edmonton, Vancouver, Hamilton, Ottawa, Toronto, Montreal, Quรฉbec
2017-07-21
Active, closed
A Randomized Trial of Pembrolizumab & Radiotherapy Versus Radiotherapy in High-Risk Soft Tissue Sarcoma of the Extremity
NCT03092323Soft Tissue Sarcoma of the Extremity
DrugsKeytruda·Pembrolizumab
Sarcoma Alliance for Research through Collaboration
Phase 2
126
Montreal
2017-07-19
Recruiting
Biology of Juvenile Myoclonic Epilepsy
NCT03400371Juvenile Myoclonic Epilepsy
King's College London
Observational
1,000
Toronto
2017-07-13
Active, closed
Endocrine Therapy With or Without Abemaciclib (LY2835219) Following Surgery in Participants With Breast Cancer
NCT03155997Breast Cancer
DrugAbemaciclib
Eli Lilly and Company
Phase 3
5,637
Ottawa, Toronto, Montreal, Quรฉbec, Sherbrooke
2017-07-12
Active, closed
EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis
NCT03042104Heart Diseases, Aortic Stenosis, Severe
Edwards Lifesciences
Not applicable
901
Hamilton, Ottawa, Toronto
2017-07-12
Active, closed
Effects of EPA in Men With Biochemical Recurrence or Progression of Prostate Cancer.
NCT03753334Prostate Cancer
CHU de Quebec-Universite Laval
Phase 2
39
Quรฉbec
2017-07-10
Recruiting
Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor
NCT03214354Sickle Cell Disease, Stem Cell Transplant Complications, Red Blood Cell Disorder, Pure Red Cell Aplasia
DrugsAlemtuzumab·Sirolimus
University of Calgary
Phase 2
12
Calgary
2017-07-05
Active, closed
Palbociclib in Patients With Metastatic Castration-Resistant Prostate Cancer
NCT02905318Prostate Cancer
DrugPalbociclib
Canadian Cancer Trials Group
Phase 2
19
Halifax, Hamilton, London, Toronto, Montreal, Regina
2017-07-04
Active, closed
Study to Allow Patients Previously Participating in a Novartis Sponsored Trial to Continue Receiving Capmatinib Treatment as Single Agent or in Combination With Other Treatments or the Combination Treatment Alone
NCT03040973Advanced Solid Tumors Which Are cMET-dependent
DrugsCapmatinib·Gefitinib·Osimertinib
Novartis Pharmaceuticals
Phase 2
29
Edmonton
2017-07-04
Active, closed
Electronic KIDCLOT Interactive Thrombosis/Thrombophilia Education; A Quality Assurance Initiative
NCT03910933Health Literacy, Anticoagulation
University of Alberta
Observational
248
Edmonton, Ottawa
2017-06-30
Active, closed
Normal Brain Imaging Database for Brain Disorder Studies
NCT03027869Healthy
University of Manitoba
Not applicable
40
Winnipeg
2017-06-28
Active, closed
A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis
NCT03165734Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis
DrugPacritinib
Swedish Orphan Biovitrum
Phase 3
407
Calgary, Edmonton, Vancouver, St. John's, Halifax, Toronto, Montreal
2017-06-26
Active, closed
Study of AG-120 (Ivosidenib) vs. Placebo in Combination With Azacitidine in Participants With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutation
NCT03173248Newly Diagnosed Acute Myeloid Leukemia (AML), Untreated AML, AML Arising From Myelodysplastic Syndrome (MDS), Leukemia, Myeloid, Acute
DrugsIvosidenib·Azacitidine
Institut de Recherches Internationales Servier
Phase 3
146
Winnipeg, Toronto
2017-06-26
Recruiting
The Role of Nutrition in Muscle Function of Bariatric Surgery Patients
NCT06680492Obesity, Diabetes, Nutrition, Physical Health, Body Composition Changes, Muscle Function, Handgrip Strength Test, Protein Metabolism
Concordia University, Montreal
Observational
75
Montreal
2017-06-23
Recruiting
Twice Daily Treatment With Amoxicillin for Non-severe Community Acquired Pneumonia.
NCT03031210Community-acquired Pneumonia
DrugAmoxicillin
St. Justine's Hospital
Phase 2/3
1,370
Montreal
2017-06-11
Active, closed
Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma
NCT03057626Recurrent Neuroblastoma, Stage 2A Neuroblastoma, Stage 2B Neuroblastoma, Stage 3 Neuroblastoma
Children's Oncology Group
Observational
376
Calgary, Edmonton, Winnipeg, Halifax, Hamilton, Kingston, Ottawa, Toronto
2017-06-05
Recruiting
3T MRI in Patients With Deep Brain Stimulation (DBS)
NCT03153670Neuro-Degenerative Disease
University Health Network, Toronto
Not applicable
250
Toronto
2017-06-01
Active, closed
REDUCE LAP-HF TRIAL II
NCT03088033Heart Failure
Corvia Medical
Not applicable
608
Hamilton
2017-06-01
Active, closed
Prolonged Continuous ECG Monitoring Prior to Transcatheter Aortic Valve Implantation
NCT03561805Aortic Valve Stenosis, Arrythmia
Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Not applicable
106
Quรฉbec
2017-06-01
Active, closed
ATTUNE Revision System in the Revision Total Knee Arthroplasty Population
NCT03153475Revision Total Knee Arthroplasty
DePuy Orthopaedics
Not applicable
400
London, Winnipeg
2017-05-30
Active, closed
Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With CD30-Positive Peripheral T-cell Lymphoma
NCT03113500Adult T-Cell Leukemia/Lymphoma, Anaplastic Large Cell Lymphoma, ALK-Negative, Anaplastic Large Cell Lymphoma, ALK-Positive, Angioimmunoblastic T-Cell Lymphoma
DrugsBrentuximab Vedotin·Doxorubicin Hydrochloride·Adriamycin·Doxorubicin
City of Hope Medical Center
Phase 2
48
Vancouver
2017-05-25
Recruiting
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
NCT03067181Childhood Extracranial Germ Cell Tumor, Extragonadal Embryonal Carcinoma, Germ Cell Tumor, Malignant Germ Cell Tumor
DrugsBleomycin·Etoposide·Cisplatin·Carboplatin
Children's Oncology Group
Phase 3
1,780
Calgary, Edmonton, Vancouver, Winnipeg, St. John's, Halifax, Hamilton, Kingston
2017-05-25
Active, closed
Atezolizumab in Treating Patients With Cancer Following Adoptive Cell Transfer
NCT02862275Hematopoietic and Lymphoid Cell Neoplasm, Metastatic Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm
DrugAtezolizumab
National Cancer Institute (NCI)
Phase 1
40
Toronto
2017-05-24
Active, closed
Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.
NCT03229200Lymphoma, B-Cell, Lymphoma, Non-Hodgkin, Leukemia, B-cell, Graft Vs Host Disease
DrugIbrutinib
Pharmacyclics Switzerland GmbH
Phase 4
297
Halifax, Toronto, Montreal
2017-05-22
Recruiting
IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy
NCT03152058High Risk Pregnancy, Pregnancy Complications, Antiphospholipid Syndrome in Pregnancy, Lupus Anticoagulant Disorder
DrugCertolizumab Pegol
David Ware Branch
Phase 2
55
Toronto
2017-05-17
Active, closed
MAGE-A4แถœยนยบยณยฒT for Multi-Tumor
NCT03132922Urinary Bladder Cancer, Melanoma, Head and Neck Cancer, Ovarian Cancer
USWM CT, LLC
Phase 1
71
Toronto
2017-05-15
Active, closed
Comparison of the Balloon-Expandable Edwards Valve and Self-Expandable CoreValve Evolut R or Evolut PRO System for the Treatment of Small, Severely Dysfunctional Surgical Aortic Bioprotheses. The 'LYTEN' Trial
NCT03520101Aortic Valve Stenosis, Regurgitation, Aortic, Prosthesis Failure
Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Not applicable
102
Quรฉbec
2017-05-10
Active, closed
Silver in Partial Thickness Pediatric Burns
NCT06971562Pediatric Burns
IWK Health Centre
Not applicable
80
Halifax
2017-05-03
Active, closed
Long Term Follow Up for CTSN Mitral Valve Repair Studies
NCT03066050Mitral Valve Insufficiency, Coronary Artery Disease
Icahn School of Medicine at Mount Sinai
Observational
368
Edmonton, Toronto, Montreal, Quรฉbec
2017-05-03
Active, closed
A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)
NCT03157128Non-Small Cell Lung Cancer, Medullary Thyroid Cancer, Colon Cancer, Any Solid Tumor
DrugSelpercatinib
Eli Lilly and Company
Phase 1/2
857
Vancouver
2017-05-02
By invitation
Molecular-Functional Imaging of Hypoxia in Childhood Sarcomas
NCT03054792Rhabdomyosarcoma, Non-Rhabdo. Soft Tissue Sarcoma
The Hospital for Sick Children
Phase 1
18
Toronto
2017-05-01
Active, closed
Cognitive Changes After Major Joint Replacement - Full Trial (Cognigram 2)
NCT03147937Postoperative Cognitive Dysfunction, Cognitive Impairment, Mild Cognitive Impairment, Delirium
Dr. Stephen Choi
Observational
505
Toronto
2017-05-01
Recruiting
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
NCT03053193Breast Cancer
Agendia
Observational
30,000
Brampton, Thunder Bay
2017-04-28
Active, closed
Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy
NCT03055013Metastatic Renal Cell Carcinoma, Sarcomatoid Renal Cell Carcinoma, Stage II Renal Cell Cancer AJCC v7, Stage III Renal Cell Cancer AJCC v7
DrugNivolumab
National Cancer Institute (NCI)
Phase 3
819
Calgary, Edmonton, Winnipeg, Moncton, Halifax, Hamilton, Kingston, London
2017-04-28
Recruiting
Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors
NCT03141021Malignant Peripheral Nerve Sheath Tumors
Washington University School of Medicine
Observational
1,050
Toronto
2017-04-28
Active, closed
A Study Of Lorlatinib Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC
NCT03052608Carcinoma, Non-Small-Cell Lung
DrugsLorlatinib·Crizotinib
Pfizer
Phase 3
296
Toronto, Montreal
2017-04-27
Recruiting
Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery
NCT03051464Stage II Rectal Cancer, Organ Preservation, Non-operative Treatment, Rectal Cancer (Stage III)
Sir Mortimer B. Davis - Jewish General Hospital
Phase 2/3
131
Montreal, Quรฉbec
2017-04-25
Recruiting
TSA Techniques in Glenohumeral OA
NCT02966886Osteoarthritis, Shoulder
Ottawa Hospital Research Institute
Not applicable
216
Ottawa
2017-04-23
Recruiting
In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps
NCT02975310Sinusitis, Nasal Polyps
Ottawa Hospital Research Institute
Not applicable
140
Vancouver, London, Ottawa, Montreal
2017-04-11
Active, closed
Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer
NCT03137771Recurrent Non-Small Cell Lung Carcinoma, Stage IV Non-Small Cell Lung Cancer
DrugsErlotinib·Taxotere·Keytruda·Pemetrexed
NRG Oncology
Phase 2
218
Edmonton, London, Ottawa
2017-04-07
Active, closed
A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL
NCT02972840Lymphoma, Mantle Cell
DrugsAcalabrutinib·Bendamustine·Rituximab
Acerta Pharma BV
Phase 3
635
Vancouver, Oshawa, Toronto, Edmonton, Greenfield Park, Halifax
2017-04-05
Active, closed
Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery
NCT03070886Stage I Prostate Adenocarcinoma AJCC v7, Stage II Prostate Adenocarcinoma AJCC v7, Stage III Prostate Adenocarcinoma AJCC v7
DrugsFlutamide·Goserelin Acetate·Degarelix·Leuprolide Acetate
NRG Oncology
Phase 2/3
612
Calgary
2017-04-05
Active, closed
An Affirmative Coping Skills Intervention to Improve Mental and Sexual Health of Sexual and Gender Minority Youth
NCT04318769Mental Health Issue, Hiv, Stigma, Social, Coping Skills
University of Toronto
Not applicable
300
Hamilton, Oakville, Toronto
2017-04-01
Active, closed
Durvalumab and Tremelimumab ยฑ Platinum-Based Chemotherapy in Patients With Metastatic Squamous or Non-Squamous NSCLC
NCT03057106Lung Cancer Metastatic
DrugsTremelimumab·Durvalumab
Canadian Cancer Trials Group
Phase 2
301
Edmonton, Surrey, Vancouver, Fredericton, Moncton, Saint John, Cambridge, Greater Sudbury
2017-03-28
Active, closed
Study of Nivolumab in Combination With Ipilimumab or Standard of Care Chemotherapy Compared to the Standard of Care Chemotherapy Alone in Treatment of Participants With Untreated Inoperable or Metastatic Urothelial Cancer
NCT03036098Urothelial Cancer
DrugsIpilimumab·Nivolumab·Gemcitabine·Cisplatin
Bristol-Myers Squibb
Phase 3
1,314
Halifax, London, Quรฉbec, Sherbrooke
2017-03-24
Active, closed
Testing the Combination of MLN0128 (TAK-228) and AZD9291 in Advanced EGFR (Epidermal Growth Factor Receptor) Mutation Positive Non-small Cell Lung Cancer
NCT02503722Metastatic Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Stage III Lung Non-Small Cell Cancer AJCC v7, Stage IIIA Lung Non-Small Cell Cancer AJCC v7
DrugsSapanisertib·Osimertinib
National Cancer Institute (NCI)
Phase 1
36
Vancouver, Toronto
2017-03-23
Recruiting
tDCS on Parkinson's Disease Cognition
NCT03025334Parkinson Disease, Mild Cognitive Impairment
University of Manitoba
Not applicable
36
Winnipeg
2017-03-22
Recruiting
Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System
NCT03067051Recurrent Prostate Cancer
DrugVerteporfin
SpectraCure AB
Phase 1/2
66
Toronto
2017-03-21
Active, closed
Mindfulness Based Eating Awareness Training for Bariatric Surgery Patients
NCT03488966Obesity, Morbid, Eating Disorder Symptom
University Health Network, Toronto
Not applicable
85
Toronto
2017-03-20
Active, closed
PSMA PET/CT for Assessment of Recurrent Prostate Cancer
NCT02899312Prostatic Neoplasms, Prostate Cancer
British Columbia Cancer Agency
Observational
2,244
Vancouver
2017-03-16
Recruiting
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
NCT03093116Locally Advanced Solid Tumors, Metastatic Solid Tumors
DrugRepotrectinib
Turning Point Therapeutics, Inc.
Phase 1/2
500
Edmonton, Vancouver, Toronto, Ontario, Ottawa
2017-03-07
Active, closed
Phase II High Dose Brachytherapy and Low Dose Rate Brachytherapy as Monotherapy in Localized Prostate Cancer
NCT02960087Prostate Carcinoma
Canadian Cancer Trials Group
Not applicable
334
London, Ottawa, Toronto, Montreal, Quรฉbec
2017-03-06
Active, closed
Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents
NCT03020030Acute Lymphoblastic Leukemia, Pediatric
DrugsDexrazoxane·Asparaginase Erwinia chrysanthemi·Pegaspargase·Ara-C
Dana-Farber Cancer Institute
Phase 3
560
Montreal, Quรฉbec
2017-03-03
Active, closed
Amino Acid Nutrition in the Critically-ill
NCT02865408Critical Illness, Inflammation, Malnutrition
Arnold Kristof
Not applicable
30
Montreal
2017-03-01
Recruiting
Parents and Children Active Together Study
NCT03055871Physical Activity
University of Victoria
Not applicable
240
Victoria
2017-03-01
Active, closed
A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors
NCT02988960Advanced Solid Tumors Cancer
DrugsABBV-927·Budigalimab
AbbVie
Phase 1
163
Toronto
2017-02-22
Active, closed
A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma
NCT03075696Non-Hodgkin's Lymphoma
DrugsGlofitamab·Tocilizumab·Obinutuzumab
Hoffmann-La Roche
Phase 1/2
940
Toronto
2017-02-21
Recruiting
Effects of Compression Stockings in Asthma Symptoms at Night
NCT03303586Asthma
University Health Network, Toronto
Not applicable
40
Toronto
2017-02-21
Active, closed
Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor
NCT03069469Advanced Malignant Neoplasm, Pigmented Villonodular Synovitis, Giant Cell Tumor of Tendon Sheath, Tenosynovial Giant Cell Tumor
DrugVimseltinib
Deciphera Pharmaceuticals, LLC
Phase 1/2
120
Montreal, Toronto
2017-02-16
Active, closed
LEADERS FREE II: BioFreedomโ„ข Pivotal Study
NCT02843633Acute Coronary Syndrome, High Bleeding Risk
Biosensors Europe SA
Not applicable
1,203
Edmonton, New Westminster, Vancouver, Victoria, Hamilton, Ottawa, Montreal, Quรฉbec
2017-02-14
Recruiting
Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy
NCT04428528Breast Cancer
Sunnybrook Health Sciences Centre
Observational
100
Toronto
2017-02-13
Recruiting
Family Habit Physical Activity Study
NCT03145688Physical Activity
University of Victoria
Not applicable
240
Victoria
2017-02-12
Active, closed
A Study of Venetoclax in Combination With Azacitidine Versus Azacitidine in Treatment Naรฏve Participants With Acute Myeloid Leukemia Who Are Ineligible for Standard Induction Therapy
NCT02993523Acute Myeloid Leukemia (AML)
DrugsAzacitidine·Venetoclax
AbbVie
Phase 3
443
Calgary, Vancouver, Hamilton, Ottawa, Toronto
2017-02-02
Active, closed
A Study of Acalabrutinib vs Investigator's Choice of Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in R/R CLL
NCT02970318Chronic Lymphocytic Leukemia
DrugsIdelalisib·Acalabrutinib·Bendamustine·Rituximab
Acerta Pharma BV
Phase 3
310
Barrie, Calgary, Montreal, Ottawa, Regina, Saint John, Toronto
2017-02-02
Recruiting
CAPRI National Juvenile Idiopathic Arthritis Registry
NCT03245801Juvenile Idiopathic Arthritis (JIA)
University of British Columbia
Observational
1,238
Calgary, Edmonton, Vancouver, Winnipeg, St. John's, Halifax, Hamilton, London
2017-02-01
By invitation
Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
NCT05514431Anesthesia, Analgesia
Mayo Clinic
Observational
1,500
Vancouver
2017-02-01
Active, closed
A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC)
NCT03006068Ulcerative Colitis (UC)
DrugUpadacitinib
AbbVie
Phase 3
950
Calgary, Edmonton, Kelowna, Victoria, Greater Sudbury, Hamilton, Ottawa, Vaughan
2017-01-31
Active, closed
A(B)VD Followed by Nivolumab as Frontline Therapy for Higher Risk Patients With Classical Hodgkin Lymphoma (HL)
NCT03033914Hodgkin Lymphoma
DrugsVinblastine·Bleomycin·Dacarbazine·Doxorubicin
Memorial Sloan Kettering Cancer Center
Phase 1/2
82
Vancouver
2017-01-25
Active, closed
Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer
NCT02954874Breast Carcinoma In Situ, Invasive Breast Carcinoma, Stage I Breast Cancer AJCC v7, Stage II Breast Cancer AJCC v6 and v7
DrugsKeytruda·Pembrolizumab
National Cancer Institute (NCI)
Phase 3
1,195
Calgary, Edmonton, Surrey, Vancouver, Moncton, Saint John, St. John's, Hamilton
2017-01-18
Active, closed
TDM Guided Early Optimization of ADAL in Crohn's Disease
NCT03261102Crohn Disease, Drug Monitoring, Inflammatory Bowel Diseases
DrugsHumira·Adalimumab
waqqas.afif
Not applicable
200
Calgary, Vancouver, London, Ottawa, Montreal, Sherbrooke
2017-01-17
Active, closed
Alberta Cancer Exercise Hybrid Effectiveness-Implementation Study
NCT02984163Neoplasms
University of Alberta
Not applicable
2,570
Calgary, Edmonton
2017-01-09
Active, closed
Standard Versus "Single Loop" Bypass After Parietal Gastrectomy
NCT07115836Obesity, Morbid, Obesity
Laval University
Not applicable
63
Quรฉbec
2017-01-06
Recruiting
PARTNER 3 Trial - Aortic Valve-in-Valve
NCT03003299Aortic Stenosis, Aortic Stenosis, Severe
Edwards Lifesciences
Not applicable
125
Vancouver
2017-01-05
Recruiting
Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting
NCT03041883Corneal Melting in Boston Keratoprosthesis Type I
Centre hospitalier de l'Universitรฉ de Montrรฉal (CHUM)
Not applicable
40
Montreal
2017-01-04
Recruiting
A Randomized Multicenter Study for Isolated Skin Vasculitis
NCT02939573Primary Cutaneous Vasculitis, Cutaneous Polyarteritis Nodosa, IgA Vasculitis, Henoch-Schรถnlein Purpura
DrugsDapsone·Azathioprine·Colchicine
University of Pennsylvania
Phase 2
90
Hamilton, Toronto, Montreal
2017-01-01
Recruiting
Retinoblastoma Patient Clinical Database and Tissue Repository
NCT04959097Retinoblastoma, Retinoblastoma Bilateral, Retinoblastoma Unilateral
Children's Hospital Los Angeles
Observational
800
Toronto
2017-01-01
Recruiting
HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease
NCT02855476Huntington's Disease
University College, London
Observational
2,500
Vancouver, Ottawa, Toronto
2017-01-01
Recruiting
Aerobic Exercise for Older Adults at Increased Risk of Alzheimer's Disease and Related Dementias
NCT03035851Alzheimer Disease, Dementia
University of Calgary
Not applicable
264
Calgary
2017-01
Active, closed
The Medtronic Harmonyโ„ข Transcatheter Pulmonary Valve Clinical Study
NCT02979587Congenital Heart Disease, Tetrology of Fallot, RVOT Anomaly, Pulmonary Regurgitation
Medtronic Heart Valves
Not applicable
86
Toronto
2017-01
Recruiting
Improving Renal Complications in Adolescents With Type 2 Diabetes Through REsearch Cohort Study (National iCARE Study)
NCT02818192Type 2 Diabetes, Proteinuria, Stress, Nephropathy
University of Manitoba
Observational
500
Winnipeg
2017-01
Recruiting
The Irrigation or No Irrigation in Simple Lacerations Trials
NCT02976480Laceration - Injury, Infection
Universitรฉ de Sherbrooke
Not applicable
1,000
Chicoutimi
2017-01
Recruiting
Clinical Transcriptomics in Systemic Vasculitis (CUTIS)
NCT03004326Cryoglobulinemic Vasculitis (CV), Drug-induced Vasculitis, Eosinophilic Granulomatosis With Polyangiitis (EGPA), IgA Vasculitis
Peter Merkel
Observational
50
Hamilton, Toronto
2017-01
Active, closed
Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer
NCT02546661Muscle Invasive Bladder Cancer
DrugsAZD4547·Vistusertib·Danvatirsen·Adavosertib
AstraZeneca
Phase 1
117
Edmonton, Vancouver, Toronto, Montreal
2016-12-28
Active, closed
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study
NCT02960022Prostate Cancer
DrugsLeuprolide Acetate·Abiraterone acetate·Enzalutamide·Prednisone
Astellas Pharma Global Development, Inc.
Phase 2
900
Kingston, Toronto, Granby, Abbotsford British Columbia, Greenville, Montreal, Oakville, Quรฉbec
2016-12-22
Active, closed
An Observational Prospective Long-term Exposure Registry of Adult Patients With Moderate-to-Severe Ulcerative Colitis
NCT02808780Ulcerative Colitis
Janssen Biotech, Inc.
Observational
535
New Westminster, Vancouver, Oshawa, Ottawa
2016-12-16
Active, closed
To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
NCT03006172Breast Cancer, Solid Tumor
DrugsInavolisib·Palbociclib·Pertuzumab·Metformin
Genentech, Inc.
Phase 1
200
Toronto
2016-12-13
Active, closed
Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme
NCT02685605Glioblastoma
DrugTemozolomide
Universitรคtsmedizin Mannheim
Phase 3
314
Montreal
2016-12-09
Recruiting
Antimicrobial Prophylaxis for Skin Colonization With Propionibacterium Acnes in Primary Open Shoulder Surgery
NCT02996656Propionibacterium Infection
DrugsCeftriaxone·Cefazolin
Universitรฉ de Montrรฉal
Not applicable
88
Montreal
2016-12
Active, closed
Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders:
NCT03100474Essential Tremor, Parkinson's Disease, Movement Disorders, Neuropathic Pain
InSightec
Observational
500
Toronto
2016-12
Active, closed
A Study of LY3200882 in Participants With Solid Tumors
NCT02937272Solid Tumor
DrugsNab-paclitaxel·Gemcitabine·Cisplatin
Eli Lilly and Company
Phase 1
223
Lai Chi Kok
2016-11-21
Recruiting
Study of Food Aversion in Patients With Anorexia Nervosa
NCT03100656Anorexia Nervosa
University of California, San Diego
Not applicable
300
Toronto
2016-11-10
Recruiting
VCRC Tissue Repository
NCT02967068Aortitis, Cutaneous Vasculitis, Eosinophilic Granulomatosis With Polyangiitis, Giant Cell Arteritis
University of Pennsylvania
Observational
1,000
Hamilton, Toronto
2016-11
Active, closed
Stereotactic Ablative Body Radiotherapy (SABR) for Oligometastases
NCT02933242Metastatic Tumors
British Columbia Cancer Agency
Not applicable
399
Prince George
2016-11
Active, closed
Composite Outcomes of Mesh vs Suture Techniques for Prolapse Repair: A Randomized Controlled Multicentre Trial
NCT02965313Pelvic Organ Prolapse
University of British Columbia
Not applicable
358
Vancouver
2016-11
Recruiting
Contingency Management as an Adjunct Treatment for Rural and Remote Disordered Gamblers
NCT02953899Gambling Disorder
University of Lethbridge
Not applicable
54
Lethbridge
2016-11
Active, closed
Home-Based CR and tDCS to Enhance Cognition in Persons With Mild Cognitive Impairment and Late Life Depression
NCT02959502Mild Cognitive Impairment, Major Depressive Disorder, Alzheimer's Dementia, Transcranial Direct Current Stimulation
Centre for Addiction and Mental Health
Not applicable
40
Toronto
2016-10-31
Recruiting
Personalized Indications for CBT and Antidepressants in Treating Depression
NCT02752542Major Depressive Disorder, Persistent Depressive Disorder
DrugPharmacotherapy
Nova Scotia Health Authority
Phase 4
80
Halifax
2016-10-31
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Canadian investigative site. Derived from ClinicalTrials.gov. Retrieved 28 September 2026. https://priyalifescience.com/clinical-trials-canada?page=61

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Canada and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 6,540 studies in total at the last sync on 26 Sep 2026, 19:55 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in Canada?

3,515 of the 6,540 studies in this register are recruiting new participants as of the 26 Sep 2026, 19:55 UTC sync. A further 629 have not yet opened recruitment, 2,212 are active but closed to new participants, and 184 are enrolling by invitation only. Eligibility for any study is decided by its study team.

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Browse trials by condition

Breast Cancer (136) Prostate Cancer (110) Cancer (75) Obesity (64) Multiple Myeloma (63) Stroke (57) Heart Failure (56) Ulcerative Colitis (43) Non-small Cell Lung Cancer (39) Type 2 Diabetes (39) Non-Small Cell Lung Cancer (38) Atrial Fibrillation (38) Healthy (36) Anxiety (35) Asthma (35)
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Browse trials by site location

Toronto (2809) Montreal (1902) Vancouver (1179) Calgary (1061) Edmonton (1017) Ottawa (872) London (871) Hamilton (809) Quรฉbec (678) Halifax (533) Winnipeg (455) Sherbrooke (265) Kingston (256) Kelowna (172) Brampton (147)
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.