Hip Dislocation, CongenitalHip Dysplasia, Congenital, NonsyndromicCongenital Dysplasia of the HipCongenital Hip DislocationCongenital Hip DisplacementCongenital Hip DysplasiaDislocation of Hip, CongenitalDislocation, Congenital HipDisplacement, Congenital HipDysplasia, Congenital HipHip Displacement, CongenitalHip, Dislocation Of, Congenital
Investigational drug(s) / intervention(s)
Observational
Observational: All groups will undergo observational data collection. No interventions will be made to patient care.
Study summary
Developmental dysplasia of the hip (DDH) is the most common hip condition affecting infants and children. DDH represents a spectrum of issues affecting the hip joint - a "ball-and-socket" joint. When the femoral head (the "ball) is seated properly in the acetabulum (the "socket"), the hip is stable and can develop normally. However, when the femoral head is not well-seated, the hip can become unstable or dislocate. This instability or dislocation of the femoral head prevents the hip joint from developing normally during infancy and early childhood. If left undetected or untreated, it can lead to debilitating complications later in life.
Development of a comprehensive, prospective international registry for all infants and children with DDH will provide the potential to impact all infants born, not only in British Columbia, but around the world. The purpose of this initiative is to identify best practices and standardize treatment and management strategies in order to optimize clinical and functional outcomes for patients with DDH. This registry includes targeted specific outcomes that will be investigated, in addition to the general collection of data on all patients diagnosed with any form of DDH up to the age of 10 years.
Eligibility
Sex
ALL
Min age
1 Minute
Max age
10 Years
Healthy volunteers
No
Inclusion Criteria:
* Between the ages of 0 and 10 years at time of initial diagnosis
* Referred for DDH screening due to specific risk factors OR diagnosed with DDH
* Diagnosis confirmed with appropriate ultrasonographic or radiographic imaging
Exclusion Criteria:
* Known or suspected neuromuscular, collagen, chromosomal or lower extremity congenital anomalies
* Teratologic hip dislocation (syndromic-associated dislocations)
* Over 10 years of age at initial diagnosis
* Received prior treatment for DDH without appropriate imaging or documentation
Primary outcome measure(s)
Development of a general, prospective DDH registry with follow-up to skeletal maturity — Until study completion in 2028 Data will be collected from patients with or at risk of DDH to create a registry. Patients will be followed up until skeletal maturity.
Identification of variation in DDH screening, diagnosis, and management protocols — Until study completion in 2028 Using data from the registry, variation in DDH screening, diagnosis, and management protocols will be identified.
Comparison of brace treatment outcomes within and across diagnostic categories — Until study completion in 2028 Using data from the registry, brace treatment outcomes within and across diagnostic categories will be compared.
Comparison of surgical treatment outcomes within and across diagnostic categories — Until study completion in 2028 Using data from the registry, surgical treatment outcomes within and across diagnostic categories will be compared.
Identification of optimal timing of both bracing and surgical treatment — Until study completion in 2028 Using data from the registry, optimal timing of both bracing and surgical treatment will be identified.
Identification and characterization of risk factors for treatment complications (i.e., AVN) — Until study completion in 2028 Using data from the registry, risk factors for treatment complications (i.e., AVN) will be identified and characterized.
Identification of predictors of the need for hip reconstructive surgery in adolescence — Until study completion in 2028 Using data from the registry, predictors of the need for hip reconstructive surgery in adolescence will be identified.
Trial sites (1)
Facility
City
Region
Status
British Columbia Children's Hospital
Vancouver
British Columbia
Recruiting
More University of British Columbia trials in Canada
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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