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Clinical Trials in Brazil / NCT07129733
Starting soon Not applicable

Oral Care Layered Enhancement for Improved Oral Hygiene in Intensive Care Units

NCT07129733 · tracked via the Priya Life Science Brazil tracker
Sponsor
Hospital do Coracao
Phase
Not applicable
Started
2025-09-01
Last updated
2025-08-19

Condition(s) studied

Mechanical VentilationInfection PreventionOral CareOral Hygiene, Oral HealthVAP - Ventilator Associated Pneumonia

Investigational drug(s) / intervention(s)

Oral hygiene bundle

Oral hygiene bundle: Implementation of the standardized oral hygiene bundle, which consists of the following key components: Standardization of materials used during the oral hygiene procedure, standardization of oral hygiene frequency, training of nursing staff involved in patient care on proper oral hygiene practices, discontinuation of routine application of chlorhexidine oral solution, and implementation of a standardized oral hygiene technique.

Study summary

The goal of the ORACLE study is to evaluate the impact of implementing a standardized oral hygiene bundle on outcomes in critically ill, mechanically ventilated patients. The primary objective is to determine whether this bundle can increase the number of ventilator-free days compared to the standard of care.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * All patients who receive mechanical ventilation in the participating intensive care units Exclusion Criteria: * Does not meet inclusion criteria

Primary outcome measure(s)

Trial sites (6)

FacilityCityRegionStatus
Santa Casa de Misericordia de Passos Passos Minas Gerais
Hospital Municipal de Maringa Maringá Paraná
Hospital da Restauracao Recife Pernambuco
Hospital Santa Cruz Santa Cruz Rio Grande do Sul
Hospital Nereu Ramos Florianópolis Santa Catarina
Hospital Leo Orsi Itapetininga São Paulo

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Other trials for the same condition

Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE) Recruiting
Swallowing Assessment for Predicting Extubation Failure in Critically Ill Patients Starting soon
Trial of Spontaneous Breathing Test Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07129733 on ClinicalTrials.gov ↗ ← All trials in Brazil