Effects of Omega-3 and Whey Protein Supplementation on Lean Mass in Older Adults

Condition(s) studied

Investigational drug(s) / intervention(s)

Placebo Group: The placebo group will receive 5 g per day of sunflower oil and 38 g per day of maltodextrin.

Whey Protein + Placebo: The whey protein + placebo group will receive 38g per day of whey and 5g per day of sunflower oil.

Omega 3 + Placebo: The omega 3 + placebo group will receive 5 g per day of fish oil and 38 g per day of maltodextrin.

Omega 3 + Whey Protein: The omega 3 + whey group will receive 5g per day of fish oil and 38g per day of protein.

Study summary

To evaluate the effect of omega-3 supplementation combined with whey protein intake on lean mass, muscle strength, metabolomic and lipidomic profiles, and biomarkers of oxidative stress and inflammation in older adults undergoing resistance exercise. Participants will be randomized into the 4 groups. The placebo group will receive 5 g per day of sunflower oil and 38 g per day of maltodextrin. The omega 3 + placebo group will receive 5 g per day of fish oil and 38 g per day of maltodextrin. The whey protein + placebo group will receive 38g per day of whey and 5g per day of sunflower oil. The omega 3 + whey group will receive 5g per day of fish oil and 38g per day of protein. All will perform the same exercise protocol for 12 weeks.

Eligibility

Primary outcome measure(s)

• Changes in lean mass (kg) using ultrasound and dual-energy X-ray absorptiometry (DXA) in postmenopausal women — up to 12 weeks

Trial sites (1)

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