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Recruiting Not applicable

Acute Power Training Effects in Older Adults

NCT07522398 · tracked via the Priya Life Science Belgium tracker
Phase
Not applicable
Started
2026-04-20
Last updated
2026-09-17

Condition(s) studied

Muscle PowerFunctional PerformanceOlder Adults (65 Years and Older)Neuromuscular FunctionPhysiological ResponsesHealthy Older Adults

Investigational drug(s) / intervention(s)

Power Training at Different Fatigue Levels

Power Training at Different Fatigue Levels: Participants perform supervised power-training exercise on a pneumatic leg press. Each participant completes three exercise sessions, each separated by approximately one week. In each session, participants perform 4 sets of leg press exercise under different fatigue conditions: A) Exercise sets are terminated when movement velocity decreases by 10%. B) Exercise sets are terminated when movement velocity decreases by 30%. C) Exercise sets are terminated at 10% velocity loss, with total work matched to the 30% condition.

Study summary

The goal of this clinical trial is to learn how older adults respond to power training when the level of fatigue during exercise is different. Power training means performing fast movements with moderate loads to improve strength, power and mobility.

The main questions the study aims to answer are:

* How does the level of fatigue during power training acutely affect strength, movement, and muscle function?
* How does it affect recovery, muscle soreness, and how hard the exercise feels?

Researchers will compare three power-training sessions with different fatigue levels to see which approach may be safest and most effective for older adults.

Participants will be healthy older adults aged 65 to 85 years. Each participant will complete three supervised exercise sessions on a leg press machine. The sessions will take place about one week apart.

During the study, participants will:

* Perform power training on a pneumatic leg press machine
* Complete strength and mobility tests before and after exercise
* Provide small blood samples to measure body responses to exercise
* Rate how hard the exercise feels
* Report muscle soreness for up to two days after exercise

The results may help researchers design safer and more effective power-training programs to improve strength, mobility, and recovery in older adults.

Eligibility

Sex
ALL
Min age
65 Years
Max age
85 Years
Healthy volunteers
Accepted
Inclusion criteria: Participants must: * Be 65 to 85 years old. * Be able to live independently and perform everyday activities without help. * Not have regularly done resistance or strength training in the past year. * Be able to understand study instructions and communicate in the study language. * Have a recent statement from their treating physician confirming that their heart and blood vessels are healthy enough to safely take part in this study. Exclusion criteria Participants will not be eligible if they have any of the following: * Unstable heart disease, neurological disease, acute infection, or fever. * Use of non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, in the 5 days before the study. * Use of whey protein, casein, or amino acid supplements in the month before the study. * Acute or chronic injuries to the legs or lower body muscles. * Any injury or condition that prevents safe leg extension exercises. * Recent lower-limb joint replacement (less than 6 months ago). * Dependence on walking aids. * Current participation in another interventional trial.

Primary outcome measure(s)

  • Maximum Voluntary Contraction (MVC) — Measurements will be taken before exercise (baseline), 5 minutes after each training session, and 24 hours after each session.
    Maximum voluntary contraction (MVC) will be assessed to determine the maximum force-generating capacity of the leg extensors using an isokinetic dynamometer (Humac Norm). Simultaneously, muscle activity will be recorded using surface electromyography (EMG; Delsys EMG system). Primary outcome metric: Peak torque (Nm) obtained from three maximal isometric trials recorded on the dynamometer, combined with EMG amplitude (µV) to quantify muscle activation. Interpretation: Higher torque values indicate greater knee extensor strength. EMG amplitude reflects the level of muscle activation during maximal voluntary effort. Interpretation: Higher force values indicate greater leg muscle strength. EMG values indicate the level of muscle activation during the maximal effort.

Trial sites (1)

FacilityCityRegionStatus
REVAL - Faculty of Rehabilitation Sciences Diepenbeek Flanders Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07522398 on ClinicalTrials.gov ↗ ← All trials in Belgium