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Clinical Trials in Belgium / NCT06517927
Recruiting Not applicable

Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10

NCT06517927 · tracked via the Priya Life Science Belgium tracker
Sponsor
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Phase
Not applicable
Started
2024-05-03
Last updated
2024-11-19

Condition(s) studied

Chemotherapy EffectDental CariesMalocclusionChildhood CancerTooth Defect

Investigational drug(s) / intervention(s)

Clinical and radiographic dental examination

Clinical and radiographic dental examination: complete clinical oral examination + intra-oral and panoramic x-rays

Study summary

To date, there are no methods for assessing the risk of oral developmental defects that could predict long-term adverse effects in childhood cancer survivors. Having such a method at our disposal would enable us to better assess the risk to develop those defects and will help us provide new prevention and treatment strategies to ensure a healthy oral development.

The aims of this study are :

* Assess the caries risk in childhood cancer survivors compared with a control group.
* Assess the dental development defects risk in childhood cancer survivors compared with a control group.

Eligibility

Sex
ALL
Min age
12 Years
Max age
36 Years
Healthy volunteers
No
Inclusion Criteria: * age below 10 at cancer diagnosis (for the CCS group). * Chemotherapy must have been used to treat the patient (For the CCS group). * The patient is 12 years old or older at the time of the follow-up appointment of the present study Exclusion Criteria: * A patient who was diagnosed and treated after 10 years old. * Patient below 12 years old at time of study recruitment * Patients with syndrome or diseases that involve teeth impairment\* * Pregnant patient * Refusal or inaptitude to undergo dental and radiographic examination

Primary outcome measure(s)

  • Assessment of the caries experience by using the Decay Missing Filled Teeth score (DMFT) — Thoughout the entire study, approximately during 2 years
    Assess the impact of the chemotherapy agents on the risk of ulterior caries development

Trial sites (1)

FacilityCityRegionStatus
Cliniques universitaires Saint-Luc Brussels Belgium Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06517927 on ClinicalTrials.gov ↗ ← All trials in Belgium