A Comparative Clinical Study Between a Collagen Matrix and Collagen Membrane as Wound Protection During Ridge Preservation ARP

Condition(s) studied

Investigational drug(s) / intervention(s)

Socket seal after alveolar ridge preservation: Socket seal is performed after ARP. Using a collagen matrix or membrane the socket is sealed, at the control (membrane) site a small pouch is made at the buccal and lingual aspect. Monofilament sutures are used to secure the respective material in place.

Study summary

Patients in need of extraction of two teeth in combination with alveolar ridge preservation will be invited to participate in intra-subject RCT on ARP. Prior to surgery, a small-field low-dose CBCT is taken.

18 patients will be included, each contributing 1 surgical site to each treatment arm.

Since this study is a intra-subject RCT randomization of the surgical site will be performed just after ARP by a coin flip. Randomization is concealed for the evaluating examiner and statistician.

After ARP the collagen matrix or collagen membrane is used to seal the coronal aspect of the extraction socket.

Soft tissue thickness in centre of the site will be determined using CBCT. Secondary outcomes include: Wound dimensions, socket wound healing score, changes in bone and soft tissue dimensions and changes in buccal soft tissue profile

Eligibility

Primary outcome measure(s)

• Soft tissue thickness in the centre of the site — pre-op, 4 months
  Changes in the soft tissue thickness at the centre of the site measured on CBCT

Trial sites (1)

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