Nurse-Led Caregiver Support for Older Adults With Advanced Lung Cancer

NCT07708870 · tracked via the Priya Life Science Taiwan tracker

Sponsor

National Taiwan University Hospital

Phase

Not applicable

Started

2025-04-08

Last updated

2026-07-16

Condition(s) studied

Non-Small Cell Lung CancerAdvanced Lung CancerCaregiver BurdenResource Utilization

Investigational drug(s) / intervention(s)

Integrating Nurse-Led and Resource Utilization-Based Caregiver Support ModelOncology Case Manager Care and Usual Care

Integrating Nurse-Led and Resource Utilization-Based Caregiver Support Model: The ICSM is a nurse-led supportive care intervention designed for older adults with advanced non-small cell lung cancer and their primary family caregivers. It includes structured education and counseling, symptom detection and management, care of aging-related problems, coping with emotional distress, problem-solving, social resource utilization, maintenance of social function during caregiving, and use of an integrated web-based or mobile messaging-based resource platform.

Oncology Case Manager Care and Usual Care: Participants receive routine oncology case manager care and usual hospital care according to standard clinical practice. This may include routine cancer care, standard follow-up, clinical consultation, and support provided through the hospital's usual care process.

Study summary

This two-phase study aims to examine the current status of older adults with newly diagnosed locally advanced or advanced non-small cell lung cancer and their primary family caregivers, and to evaluate the effects of the Integrating Nurse-Led and Resource Utilization-Based Caregiver Support Model (ICSM). Phase I is a cross-sectional correlational study assessing distress, unmet care needs, resource awareness and utilization, social support, and health promotion practice. Phase II is a two-group randomized controlled trial comparing ICSM plus oncology case manager care with oncology case manager care and usual hospital care. The intervention includes nurse-led education and counseling, symptom management, emotional coping, problem-solving, social resource use, caregiving activity arrangement, and use of a web-based or LINE-based integrated resource system.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: Patient inclusion criteria: * Older adults with newly diagnosed locally advanced or advanced non-small cell lung cancer. * Stage III or stage IV non-small cell lung cancer. * Aware of their cancer diagnosis. * Preparing to receive anti-cancer medical treatment. * Able to communicate verbally and complete study assessments. * Willing to participate in the study and provide written informed consent. Caregiver inclusion criteria: * Adult aged 18 years or older. * Identified by the eligible patient as the fixed primary family caregiver. * Able to participate in the study together with the patient as a patient-caregiver dyad. * Willing to participate in the study and provide written informed consent. Exclusion Criteria: Patient exclusion criteria: \- Severe cognitive impairment that prevents completion of study questionnaires or assessments. Caregiver exclusion criteria: * Unable to communicate sufficiently to complete study assessments. * Unable or unwilling to provide written informed consent.

Primary outcome measure(s)

Change in Caregiver Quality of Life as Measured by the Caregiver Quality of Life Index-Cancer (CQOLC) — Baseline, 2 weeks, 1 month, 3 months, 6 months, and 12 months after the first treatment
Caregiver quality of life will be assessed using the Caregiver Quality of Life Index-Cancer (CQOLC). The CQOLC is a 35-item instrument using a 5-point Likert-type scale from 0 to 4 to assess quality of life among family caregivers of patients with cancer, including physical, emotional, family, and social functioning. The total score ranges from 0 to 140, with higher scores indicating better caregiver quality of life after reverse scoring of negatively worded items.

Trial sites (2)

Facility	City	Region	Status
National Taiwan University Hospital	Taipei	Taipei	Recruiting
National Taiwan University Cancer Center	Taipei	Taipei	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07708870 on ClinicalTrials.gov ↗ ← All trials in Taiwan