This study aims to investigate the expression level of SLC25A48, a mitochondrial choline transporter, in peripheral blood mononuclear cells of patients with chronic obstructive pulmonary disease, and to analyze its correlation with inflammatory markers and choline metabolic byproducts.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* pre-COPD or COPD stages I-IV as per the 2023 GOLD guidelines (case group)
* healthy individuals without chronic diseases or major medical conditions
Exclusion Criteria:
* diagnosed with neuromuscular diseases
* experienced respiratory disease exacerbation requiring emergency care or hospitalization in the past three months
* assessed by a physician to have severe malnutrition or a significantly low BMI
* continuously taking folic acid supplements
* willing to receive or have already received self-paid nutrition clinic services at this hospital
Primary outcome measure(s)
expression of SLC25A48 — one day the expression level of SLC25A48 in mitochondria isolated from peripheral blood mononuclear cells
Trial sites (2)
Facility
City
Region
Status
Cardinal Tien Hospital
New Taipei City
Taiwan
Not Yet Recruiting
Fu Jen Catholic University Hospital, Fu Jen Catholic University
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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