Artificial Intelligence (AI)Artificial Intelligence (AI) in DiagnosisHypertension, Pulmonary
Investigational drug(s) / intervention(s)
AI-ECG Guidance
AI-ECG Guidance: Participants undergo screening using the AI-ECG system. Those identified as high-risk for pulmonary hypertension receive echocardiography to confirm the diagnosis and guide subsequent management.
Study summary
This study aims to validate the use of an artificial intelligence-enabled electrocardiogram (AI-ECG) to screen for elevated PAP. We hypothesize that the AI-ECG model can early identify patients with pulmonary hypertension in high-risk patients, prompting further evaluation through echocardiography, potentially resulting in improving cardiovascular outcomes.
Eligibility
Sex
ALL
Min age
50 Years
Max age
85 Years
Healthy volunteers
No
Inclusion Criteria:
* Men or women, ≥ 50 to 85 years of age
* At least one 12-lead ECG within 3 months
Exclusion Criteria:
* A diagnosis of PH WHO Groups 1, 2, 3, 4, or 5
* A diagnosis of hypertrophic cardiomyopathy, restrictive cardiomyopathy, constrictive pericarditis, cardiac amyloidosis, or infiltrative cardiomyopathy
* Prior heart, lung, or heart-lung transplants
* Any systolic pulmonary artery pressure \>50 mmHg by echocardiography before
* Echocardiography in 3 months before index ECG
Primary outcome measure(s)
Pulmonary arterial pressure > 50 mmHg — 90 days The composite endpoint is defined as detecting pulmonary hypertension \> 50mmHg by echocardiography, indicating high risk for pulmonary hypertension.
Trial sites (1)
Facility
City
Region
Status
National Defense Medical Center
Taipei
Taiwan
Recruiting
More National Defense Medical Center, Taiwan trials in Taiwan
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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