Efficacy of NSAID Peritendinous Injection for Acute Tendinitis

Condition(s) studied

Investigational drug(s) / intervention(s)

Peritendinous NSAID injection: Peritendinous NSAID (parecoxib) injection

Control group (placebo): Normal saline mixed with local anesthetics injection

Study summary

This study evaluates whether NSAID peritendinous or ligament injections at acute sprain sites can relieve pain and restore function.

Forty patients will be randomly assigned to either the injection or oral NSAID group. Pain will be assessed subjectively using the Numeric Pain Rating Scale and objectively through pressure pain threshold measurements. Functional outcomes (DASH for the upper limb, FADI for the lower limb) will be evaluated before treatment and at 3 days, 1 week, and 4 weeks post-treatment.

Eligibility

Primary outcome measure(s)

• Numeric Pain Rating Scale — Baseline, at 12 hours post-injection, and on each day from 1 to 7 days after the injection.
  The 11-point Numeric Rating Scale (NRS) is a subjective pain assessment tool that ranges from 0 to 10. A score of '0' indicates the complete absence of pain (e.g., "no pain"), while a score of '10' represents the most severe pain imaginable (e.g., "pain as bad as you can imagine" or "worst pain imaginable"). This scale allows individuals to quantify their pain intensity, facilitating communication between patients and healthcare providers for better pain management.

Trial sites (1)

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