This trial hypothesized that novel laser refractive surgery techniques (LASIK, KLEx) or laser-assisted cataract surgery (FLACAS) could suppress postoperative inflammation and improve recovery in patients by reducing oxidative stress generated by the surgical procedure. It is also intended to verify whether the new laser technology is necessary for clinical use in groups with low antioxidant activity through the detection of antioxidant activity in the eyes of patients.
Eligibility
Sex
ALL
Min age
20 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* at least 20 years old
* corneal refractive surgery or cataract surgery patients
Exclusion Criteria:
* patients with eye infections
* presence of severe retinal disease
* presence of severe eye injury or severe ptosis
Primary outcome measure(s)
TAC in tears at 1 week — Before the operation and 1 week after surgery. Change of Total Antioxidant Capacity (TAC) from Baseline to 1 week after surgery.
TAC in tears at 1 month — Before the operation and 1 month after surgery. Change of Total Antioxidant Capacity (TAC) from Baseline to 1 month after surgery.
TAC in tears at 2 months — Before the operation and 2 months after surgery. Change of Total Antioxidant Capacity (TAC) from Baseline to 2 months after surgery.
TAC in tears at 3 months — Before the operation and 3 months after surgery. Change of Total Antioxidant Capacity (TAC) from Baseline to 3 months after surgery.
AA in tears at 1 week — Before the operation and 1 week after surgery. Change of Ascorbic Acid (AA) from Baseline to 1 week after surgery.
AA in tears at 1 month — Before the operation and 1 month after surgery. Change of Ascorbic Acid (AA) from Baseline to 1 month after surgery.
AA in tears at 2 months — Before the operation and 2 months after surgery. Change of Ascorbic Acid (AA) from Baseline to 2 months after surgery.
AA in tears at 3 months — Before the operation and 3 months after surgery. Change of Ascorbic Acid (AA) from Baseline to 3 months after surgery.
ROS in tears at 1 week — Before the operation and 1 week after surgery. Change of Reactive Oxygen Species (ROS) from Baseline to 1 week after surgery.
ROS in tears at 1 month — Before the operation and 1 month after surgery. Change of Reactive Oxygen Species (ROS) from Baseline to 1 month after surgery.
ROS in tears at 2 months — Before the operation and 2 months after surgery. Change of Reactive Oxygen Species (ROS) from Baseline to 2 moths after surgery.
ROS in tears at 3 months — Before the operation and 3 months after surgery. Change of Reactive Oxygen Species (ROS) from Baseline to 3 months after surgery.
TAC in aqueous humor at the next day — Before the operation and one day after surgery. Change of Total Antioxidant Capacity (TAC) in aqueous humor from Baseline to one day after surgery
AA in aqueous humor at the next day — Before the operation and one day after surgery. Change of Ascorbic Acid (AA) in aqueous humor from Baseline to one day after surgery
ROS in aqueous humor at the next day — Before the operation and one day after surgery. Change of Reactive Oxygen Species (ROS) in aqueous humor from Baseline to one day after surgery
Trial sites (2)
Facility
City
Region
Status
Taipei Nobel Eye Clinic
Taipei
Taiwan
Recruiting
Chang Gung Memorial Hospital
Taoyuan
Taiwan
Recruiting
More Chang Gung Memorial Hospital trials in Taiwan
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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