EEG Brain OscillationsAlzheimer's Disease (AD)Cognitively Normal Older Adults
Investigational drug(s) / intervention(s)
Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA)
Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA): Participants will receive light stimulation using the Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA) for 1 hour per day, 7 days a week, over 4 weeks, for a total of 28 hours.
Study summary
This study aims to evaluate the effects of endogenous gamma non-flickering light stimulation on resting-state EEG rhythms and cognitive function in cognitively healthy older adults. Specifically, it will assess the immediate and long-term effects of this stimulation on brainwave activity and cognitive performance. The study will explore the potential of gamma light stimulation as a non-pharmacological intervention for cognitive decline in aging populations.
Eligibility
Sex
ALL
Min age
55 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* 1\. Age over 55 years old.
* 2\. The Cognitive Abilities Screening Instrument (CASI) score is within normal ranges adjusted for age and education.
* 3\. Participants have no history of severe neurological or psychiatric disorders (such as stroke, epilepsy, depression, migraine, etc.) that could affect cognitive function.
* 4\. Participants have not used drugs that may affect cognitive function (e.g., benzodiazepines, anticholinergic medications, etc.).
* 5\. Participants with normal or corrected vision (e.g., glasses or contact lenses) to normal levels.
* 6\. Voluntary to sign the Informed Consent Form.
Exclusion Criteria:
* 1\. Participants enrolled in any cognitive enhancement study within the past two months.
* 2\. Participants with a history of disease that could affect cognitive function (e.g., cancer, autoimmune diseases, etc.).
* 3\. Pregnant, or planning to become pregnant.
Primary outcome measure(s)
Changes in gamma brain oscillations. — baseline (T1), post one-hour intervention (T2), post one-month intervention (T3) Gamma (31-100Hz) brain oscillations obtained through resting-state EEG will evaluate the changes of gamma light stimulation intervention.
Trial sites (1)
Facility
City
Region
Status
Chang Gung University
Taoyuan
Guishan
Recruiting
More Chang Gung Memorial Hospital trials in Taiwan
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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