This study combines data from two trials testing acupuncture (ACUDES) and a Chinese herbal tea bag TBDESJS for Dry Eye Syndrome and Sjögren's syndrome. Both treatments improved tear production. Researchers will now analyze participants' blood remaining samples and other data to understand how these therapies work. They will use advanced methods to identify tiny RNA molecules and immune system activity. This integrated approach aims to explain how acupuncture and TBDESJS improve dryness and support their use in managing these conditions.
Eligibility
Sex
ALL
Min age
20 Years
Max age
75 Years
Healthy volunteers
Accepted
Dry eye syndrome
* Inclusion Criteria: aged between 20 and 75 years Schirmer's test less than 10 mm/5 min
* Exclusion Criteria: Pregnancy With eye inflammation or infectious eye disease Accepted operation of eye
Sjögren's syndrome
* Inclusion Criteria: primary or secondary SS aged between 20 and 75 years fulfilled the 2002 American-European Consensus Criteria for SS (AECG) had no abnormal findings of immune, liver, kidney, or blood function evaluations.
* Exclusion Criteria: a history of alcohol abuse, diabetes mellitus, or major life-threatening condition pregnancy or breastfeeding steroid pulse therapy within three months prior to the commencement of our study.
non AIDDES Healthy Controls
* Inclusion Criteria: aged between 20 and 75 years without any Chronic disease
* Exclusion Criteria: any Sjögren's syndrome or Dry eye syndrome.
Primary outcome measure(s)
Schirmer's test — 8 weeks Dry eye syndrome (DES) and Sjögren's syndrome (SJS) take the Schirmer's test.
Ocular Surface Disease Index (OSDI) — 8 weeks Dry eye syndrome (DES) and Sjögren's syndrome (SJS) take the OSDI(Ocular Surface Disease Index).
Trial sites (1)
Facility
City
Region
Status
Ching-Mao Chang
Taipei
Taiwan
More Taipei Veterans General Hospital, Taiwan trials in Taiwan
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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