Observational Study for Left Main Disease Treatment

NCT01341327 · tracked via the Priya Life Science Taiwan tracker

Sponsor

Seung-Jung Park

Phase

Observational

Started

2007-07

Last updated

2026-03-20

Condition(s) studied

Coronary Artery Disease

Study summary

The purpose of this study is to observe clinical courses for long-term in patients with unprotected LMCA disease and to evaluate comparative results of medical treatment, coronary stenting with drug-eluting stents, and CABG for the treatment of an unprotected LMCA stenosis in the "real world" daily practice.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Significant unprotected left main stenosis (\>50% by visual estimation) * The LMCA is considered unprotected if there are no patent coronary artery bypass grafts to the left anterior descending artery or the left circumflex artery. * No limitation of clinical or lesion characteristics * Age \>18 years * The patient or guardian agrees to the study protocol and the schedule of clinical follow-up, and provides informed, written consent, as approved by the appropriate Institutional Review Board/Ethics Committee of the respective clinical site. Exclusion Criteria: * Protected left main stenosis

Primary outcome measure(s)

Composite event rate of death, myocardial infarction, Target Vessel Revascularization or cerebrovascular event — 2-year
A composite endpoint is an endpoint that is a combination of multiple clinical endpoints. An event that is considered to have occurred if any one of several different events is observed.

Trial sites (42)

Facility	City	Region	Status
Zhongshan Hospital	Shanghai	China	Recruiting
Sarawak General Hospital	Kuching	Malaysia	Recruiting
Hallym University medical center	Anyang	South Korea	Recruiting
Soonchunhyang University Hospital, Buchen	Bucheon-si	South Korea	Terminated
The Catholic University of Korea, Bucheon ST.Mary's Hospital	Bucheon-si	South Korea	Terminated
Inje University Busan Paik Hospital	Busan	South Korea	Recruiting
Soonchunhyang University Hospital, Cheonan	Cheonan	South Korea	Recruiting
St.Mary's Catholic Medical Center	Cheongju-si	South Korea	Terminated
Daegu Catholic University Medical Center	Daegu	South Korea	Recruiting
Keimyung University Dongsan Medical Center	Daegu	South Korea	Recruiting
Yeungnam University Medical Center	Daegu	South Korea	Terminated
Chungnam National University Hospital	Daejeon	South Korea	Recruiting
The Catholic University of Korea, Daejeon ST.Mary's Hospital	Daejeon	South Korea	Terminated
Gangneung Asan Medical Center	Gangneung	South Korea	Recruiting
Chonnam National University Hospital	Gwangju	South Korea	Recruiting
National Health Insurance Service Ilsan Hospital	Ilsan	South Korea	Terminated
St.Mary's Catholic Medical Center	Inchon	South Korea	Terminated
Chonbuk National University Hospital	Jeonju	South Korea	Recruiting
Presbyterian Medical Center	Jeonju	South Korea	Recruiting
Kwangju Christian hospital	Kwangju	South Korea	Recruiting
Pusan Natioanal University Hospital	Pusan	South Korea	Recruiting
Bundang CHA Hospital	Seongnam	South Korea	Terminated
Asan Medical Center	Seoul	South Korea	Recruiting
Dongguk University Medical Center	Seoul	South Korea	Recruiting
Gangnam Severance Hospital	Seoul	South Korea	Recruiting
Kangbuk samsung hospital	Seoul	South Korea	Recruiting
Kangdong Sacred Heart Hospital	Seoul	South Korea	Recruiting
Korea University Anam hospital	Seoul	South Korea	Recruiting
Korea University Guro Hospital	Seoul	South Korea	Recruiting
Seoul National University Boramae Medical Center	Seoul	South Korea	Recruiting
Seoul National University Hospital	Seoul	South Korea	Recruiting
Seoul Veterans Hospital	Seoul	South Korea	Terminated
St.Mary's Catholic Medical Center	Seoul	South Korea	Terminated
The Catholic University of Korea, ST. Paul's Hospital	Seoul	South Korea	Terminated
The Catholic University of Korea, Yeouido ST. Mary's Hospital	Seoul	South Korea	Terminated
Yonsei University Medical Center	Seoul	South Korea	Terminated
Ajou University Hospital	Suwon	South Korea	Terminated
The Catholic University of Korea, ST. Vincent's Hospital	Suwon	South Korea	Recruiting
Ulsan University Hospital	Ulsan	South Korea	Recruiting
Wonju Christian Hospital	Wŏnju	South Korea	Recruiting

+ 2 more sites — see the full list on the official registry below.

More Seung-Jung Park trials in Taiwan

Fractional Flow Reserve Versus Angiography for Treatment-Decision and Evaluation of Significant Left MAIN Coronary Artery Disease Recruiting

The DECISION-CTO Extended 10 Y Follow-up Recruiting

Other trials for the same condition

Safety and Preliminary Effectiveness Study of Mesenchymal Stem Cells, HeXell-2020, in Patients With Stable Coronary Artery Disease Recruiting

Randomization of Single vs Multiple Arterial Grafts Recruiting

Drug-Coated Balloon vs. Drug-Eluting Stent for Clinical Outcomes in Patients With Large Coronary Artery Disease Active, not recruiting

Fractional Flow Reserve Versus Angiography for Treatment-Decision and Evaluation of Significant Left MAIN Coronary Artery Disease Recruiting

The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial Active, not recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT01341327 on ClinicalTrials.gov ↗ ← All trials in Taiwan