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Clinical Trials in Switzerland / NCT05865314
Recruiting Not applicable

Optimised Nutritional Therapy and Early Physiotherapy in Long Term ICU Patients (NutriPhyT Trial)

NCT05865314 · tracked via the Priya Life Science Switzerland tracker
Sponsor
HEIDEGGER CP
Phase
Not applicable
Started
2023-05-01
Last updated
2025-08-12

Condition(s) studied

Critical IllnessICU Acquired WeaknessMalnutrition

Investigational drug(s) / intervention(s)

Optimisation of nutrition therapy coupled with early mobilisationStandard care

Optimisation of nutrition therapy coupled with early mobilisation: Optimisation of nutrition therapy coupled with early mobilisation with: * Optimisation of nutrition therapy during ICU stay * Optimisation of physiotherapy during ICU stay * Better communication and closer collaboration between physiotherapy and nutrition teams. * Optimisation of continuity of the care.

Standard care: Patients will receive nutritional therapy and mobilisation according to local standard procedures.

Study summary

Due to medical advances and quality of care, mortality in adult intensive care units (ICUs) has decreased significantly in recent years, leading to a significant increase in the number of patients with high rehabilitation needs on discharge from the ICU.

A specific management by a multidisciplinary team has been set up since 2017 at the Geneva-ICU for long-stay patients (hospitalised ≥ 7 days).

This study aim to assess whether an optimization of the nutritional therapy coupled with an early mobility during and after the ICU stay allows an improvement in the muscle function at hospital discharge compared to patients receiving the standard care.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: Any patient admitted to the adult ICU : * ≥18 years old * On mechanical ventilation with an expected length of stay ≥ 7 days * Requiring artificial nutrition (enteral and/or parenteral nutrition) Exclusion Criteria: Therapeutic withdrawal Pregnant or breastfeeding patients Neurological disorders with motor deficits: * New or pre-existing neuromuscular or nervous system disease * Spinal cord injury Severe polytrauma of the lower limbs (amputation etc.) Non-independent ambulation (including walking aids) before ICU admission For organizational reasons not allowing follow-up : * Transfer to another ICU * Patient living abroad from Switzerland * Patient living in nursing homes preceding to ICU admission * Incarcerated patients * Intellectual/cognitive disabilities or language barrier, limiting ability to follow the instructions

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Service of Intensive Care, Geneva University Hospital, Geneva Canton of Geneva Recruiting

More HEIDEGGER CP trials in Switzerland

Trial on the Impact of Indirect Calorimetry-Guided Nutritional Support on Patient-Centered Outcomes in Critically Ill Patients - The OPTICal Study Recruiting

Other trials for the same condition

Trial on the Impact of Indirect Calorimetry-Guided Nutritional Support on Patient-Centered Outcomes in Critically Ill Patients - The OPTICal Study Recruiting
Individualized Analgesia in the Intensive Care Unit With a New Pain Assessment Bundle and Protocolized Analgesia Adjustments Starting soon
Maintaining Immune and Mitochondrial Functions in Old Adults With SAfe Nutrition. Recruiting
Effect of Continued Nutritional Support at Hospital Discharge on Mortality, Frailty, Functional Outcomes and Recovery Recruiting
A Nutrition and Exercise Program With Olanzapine Compared to Olanzapine Alone: A Trial in Patients With Advanced Tumors Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05865314 on ClinicalTrials.gov ↗ ← All trials in Switzerland