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Clinical Trials in Switzerland / NCT02105844
Active, not recruiting Observational

Swiss Atrial Fibrillation Cohort Study

NCT02105844 · tracked via the Priya Life Science Switzerland tracker
Phase
Observational
Started
2014-03
Last updated
2025-07-09

Condition(s) studied

Atrial Fibrillation

Study summary

Swiss-AF is a prospective observational, multicentric cohort study in Switzerland. Overall, 2600 patients with documented atrial fibrillation aged \>65 years will be included and followed on a yearly basis.

Yearly clinical examinations include a detailed questionnaire on personal characteristics, a resting electrocardiogram, neurocognitive function tests and questionnaires on disability and quality of life. Blood sampling and brain magnetic resonance imaging are scheduled at baseline and after 2 years of follow-up.

The main study aims of this long term prospective study are to increase our knowledge on structural brain damage and its changes over time in patients with atrial fibrillation, to gain additional insights on the incidence and underlying mechanisms of cognitive decline in patients with atrial fibrillation and to evaluate the interrelationships of structural and functional brain damage in this population.

Eligibility

Sex
ALL
Min age
45 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * atrial fibrillation documented within the last 24 months * age \>=45 years Exclusion Criteria: * acute illness * inability to provide informed consent * Only short episodes of reversible forms of atrial fibrillation

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
University Hospital Basel Canton of Basel-City

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Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT02105844 on ClinicalTrials.gov ↗ ← All trials in Switzerland