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Clinical Trials in Sweden / NCT06919185
Starting soon Observational

Short- and Long-term Effects of Robot-assisted Plication in Diaphragmatic Paralysis

NCT06919185 · tracked via the Priya Life Science Sweden tracker
Sponsor
Uppsala County Council, Sweden
Phase
Observational
Started
2025-05
Last updated
2025-04-11

Condition(s) studied

Diaphragmatic PlicationDiaphragmatic ParalysisDiaphragmatic Eventration

Study summary

Diaphragmatic paralysis may lead to severe symptoms such as breathlessness and reduced physical capacity.

Diaphragmatic plication using Robotic-Assisted Thoracic Surgery (RATS) is a minimally invasive surgical technique developed to improve lung function by correcting diaphragmatic elevation.

While its benefits have been reported in retrospective reports, prospective studies are lacking.

This prospective observational cohort study aimsto evaluate the short- and long-term effects of robot-assisted diaphragmatic plication on subjective breathlessness, physical performance, lung function, blood gases, and imaging findings at five Swedish university hospitals: Gothenburg, Linköping, Lund, Umeå, and Uppsala.

Patients will be assessed preoperatively and postoperatively after one to three months and after one and three years.

Eligibility

Sex
ALL
Min age
18 Years
Max age
85 Years
Healthy volunteers
No
Inclusion Criteria: * Patients with symptomatic unilateral diaphragmatic paralysis persisting for ≥1 year * Patients are scheduled for RATS at thoracic surgery clinics in five Swedish university hospitals (Gothenburg, Linköping, Lund, Umeå, and Uppsala). Exclusion Criteria: * Inability to complete forms in Swedish * Neuromuscular disease as the cause of diaphragmatic paralysis * Other significant causes of dyspnea * Impaired physical capacity from other causes than diaphragmatic paralysis.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Department of Medical Sciences, Lung-, Allergy-, and Sleep Research, Uppsala University/Uppsala University Hospital Uppsala Sweden

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06919185 on ClinicalTrials.gov ↗ ← All trials in Sweden