Perioperative Depression, an Observational Cohort Study

Condition(s) studied

Study summary

This observational cohort study studies two aspects of perioperative depression.

First, it examines the postoperative morbidity and mortality among patients with preoperative depression.

Secondly, in a subset of patients without signs of preoperative depression, the investigators describe the riskfactors for development of de-novo postoperative depression.

Eligibility

Primary outcome measure(s)

• Mortality — 30/60/90/365-day mortality
  Death after index surgery, time frames (see below)
• Days At Home Alive at 30 days after surgery — 30 days
  DAH-30 is calculated using mortality and hospitalisation data from the date of the index surgery (= Day 0). For example, if a patient died on day 2 after their surgery whilst still an inpatient, they would be assigned zero (0) days at home; if a patient was discharged from hospital on Day 6 after surgery but was subsequently re-admitted for 4 days before their second hospital discharge, then they would be assigned a DAH-30 value of 20. If a patient has complications and spends 16 days in hospital, and then is transferred to a nursing facility for rehabilitation, and spend 24 days there before finally being discharged to their own home, they would be assigned a DAH-30 value of zero (0), even though 30-16-24 = -10 because the minimum value of DAH-30 should be zero. If a patient dies within 30 days of surgery, irrespective of whether they have spent some time at home, DAH-30 will be scored as zero (0). That is, DAH-30 captures the impact of any complications after surgery.

Trial sites (1)

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