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Clinical Trials in Sweden / NCT05904327
Active, not recruiting Observational

Circulating Biomarkers in Oropharyngeal Cancers

NCT05904327 · tracked via the Priya Life Science Sweden tracker
Phase
Observational
Started
2020-12-01
Last updated
2023-06-15

Condition(s) studied

Oropharynx Squamous Cell CarcinomaOropharynx CancerTonsillar CancerBase of the Tongue Carcinoma

Study summary

The goal of this observational longitudinal study is to learn about circulating tumor Human Papilloma Virus-DNA (ctHPV-DNA) as a biomarker for HPV positive oropharyngeal cancer and cancer of unknown primary of the head and neck. The main questions it aims to answer are:

* Can ctHPV-DNA be used for treatment evaluation in HPV positive oropharyngeal cancer and cancer of unknown primary of the head and neck?
* Can circulating HPV-DNA be used as a biomarker for recurrent disease during surveillance?

Participants will be asked to leave plasma samples at diagnose, at the end of treatment and at every clinical follow-up.

The patients are there own controls.

Eligibility

Sex
ALL
Min age
—
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Oropharyngeal cancer * Cancer of unknown primary in the head and neck Exclusion Criteria: * Previous treatment of cancer in the oropharynx. * Previous treatment of unknown primary tumor. * Remote metastases * Patients unwilling or unable to comply with the study protocol and follow-up schedule

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Anna Oldaeus Almerén Örebro Sweden

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05904327 on ClinicalTrials.gov ↗ ← All trials in Sweden