Can the Use of a Next Generation Partograph Improve Neonatal Outcomes? (PICRINO)

Condition(s) studied

Investigational drug(s) / intervention(s)

WHOs Labour care guide: Guidelines for monitoring labor progress, the WHOs LCG

Study summary

The overall aim is to evaluate the impact of the use of two different guidelines for monitoring labor progress, the WHOs LCG versus standard care, on neonatal and maternal outcomes. The hypothesis is that the use of LCG will reduce adverse neonatal outcomes and decrease the number of intrapartum Cesarean sections compared with standard care.

Secondly, other perinatal interventions and complications will be compared between the LCG and standard care groups, as well as economic considerations. This will be investigated using a multicenter, stepped-wedge cluster randomized trial design.

In addition, the project will explore a series of quantitative and qualitative research questions to gain in-depth knowledge about experiences and perceptions about childbirth and the use of LCG. These research questions will be investigated using questionnaires, focus group and individual interviews with providers, partners and women that have gone through childbirth.

Eligibility

Primary outcome measure(s)

• Adverse neonatal outcome — 12 weeks up to 18 months
  a composite outcome of perinatal mortality and neonatal morbidity. Neonatal morbidity will include five-minute Apgar score \<7, hypoxic ischemic encephalopathy II-III, intracranial hemorrhage, neonatal seizures, meconium aspiration syndrome, and admission to a neonatal unit.
• The rate of intrapartum cesarean section — 12 weeks up to 18 months
  The rate of intrapartum cesarean section

Trial sites (24)

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