Preventive Physical Activity Intervention in Head and Neck Cancer

NCT05432297 · tracked via the Priya Life Science Sweden tracker

Sponsor

Sahlgrenska University Hospital

Phase

Not applicable

Started

2023-01-02

Last updated

2026-04-23

Condition(s) studied

Head and Neck NeoplasmsPhysical Inactivity

Investigational drug(s) / intervention(s)

Preventive physical exercise

Preventive physical exercise: Daily physical activity depending on daily condition

Study summary

The study includes patients with tumors of the oropharynx, larynx and hypopharynx scheduled to receive radiotherapy with curative intent (+/- chemotherapy). The patients will be randomized into either an intervention group (performing a preventive physical activity protocol before and during radiotherapy) or a control group not performing a specified physical exercise protocol. All patients will be in contact with with a speech language pathologist or a physical therapist weekly during radiotherapy. The study is expected to improve physical function and quality of life during and after oncologic treatment

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Head and neck cancer (tumors of the oropharynx, pharynx, hypopharynx and larynx) * Receiving radiohterapy (+/- chemotherapy) with curative intent Exclusion Criteria: * Surgery due to head and neck cancer * Previous treatment for head and neck cancer * Tracheostomized patients * Inability to perform exercise intervention * Inability to perform part of 6-minute walking test * Inability to independently fill out questionnaires in Swedish * Previous neurologic or neuromuscular disease

Primary outcome measure(s)

Objectively measured physical activity — Up to 12 months
Measured with an accelerometer. Measures time spent in different activities i minutes/day.
Subjectively measured physical activity - Saltin-Grimby — Up to 12 months
Measured with the Saltin-Grimby physical activity level scale and the International Physical Activity Questionnaire.
Subjectively measured physical activity (IPAQ) — Up to 12 months
Measured with the International Physical Activity Questionnaire

Trial sites (1)

Facility	City	Region	Status
Sahlgrenska University Hospital	Gothenburg	Sweden	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05432297 on ClinicalTrials.gov ↗ ← All trials in Sweden