Not applicable- observational study: Fecal sample collection
Study summary
Recent research suggests a significant link between gut microbiota and anastomotic leakage (AL) in colorectal surgery. Patients who develop AL have a higher abundance of bacteria from the Lachnospiraceae family and lower microbial diversity.
Considering the bibliographic data, our main interest is to analyze the microbial population of patients in our social environment and then look for differences in the microbiome between those who have suffered an anastomotic dehiscence (around 8-9% according to the results of our hospital's Surgery Department) and those who have not.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Patients who have undergone colorectal intestinal anastomosis.
* Signing of the informed consent form.
* Age ≥18 years with good functional status.
* Availability for postoperative follow-up.
Exclusion Criteria:
* Emergency surgery.
* Intra-abdominal sepsis or previous dehiscence.
* Severe immunosuppression.
* Use of antibiotics in the 3 months prior to preoperative preparation.
* Pregnancy or breastfeeding.
Primary outcome measure(s)
Understand the patient's microbiome — From enrollment to a month post surgery To understand the microbiome of patients undergoing colorectal surgery and the effect of current surgical preparation on the microbiota in our local population.
Trial sites (1)
Facility
City
Region
Status
University Hospital Fundación Jiménez Díaz
Madrid
Spain
Recruiting
More Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz trials in Spain
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.
