Use of PRP for the Healing of Grade III Ulcers

Condition(s) studied

Investigational drug(s) / intervention(s)

PRP group: The PRP will be injected into the wound bed, unlike in other studies where it has been used only as a gel.

Classic treatment: Standard care for patients in the control group: Aquacel + Gel every 48 hours

Study summary

Treatment with platelet-rich plasma (PRP) consists of extracting a small amount of blood from the patient himself, which is later processed by centrifugation to obtain a fraction rich in platelets. It will be done on weekly or fortnightly blood extraction procedure, depending on the process. Between 1-3 sterile citrate collection tubes will be used, which may vary depending on the size of the ulcer. Each tube can contain approximately 8-10ml of blood and the procedure is carried out under aseptic conditions and with material from a single use Once the sample has been centrifuged, the blood plasma will be extracted and the concentrate obtained will be applied directly on the wound or ulcer with the objective of stimulating and accelerating healing by means of growth factors.

This procedure is used as complementary therapy in chronic ulcers or with difficulty in healing, such as they can be venous, arterial, pressure or diabetic foot ulcers.

Eligibility

Primary outcome measure(s)

• Change in ulcer diameter at 30, 60, and 90 days — At the beginning of patient inclusion and at 30, 60, and 90 days from the start of therapy

Trial sites (1)

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