Residual Neuromuscular Block in the Post-Anesthetic Unit and Postoperative Complications

Condition(s) studied

Investigational drug(s) / intervention(s)

Train-of-four: Patients submitted to general anesthesia with neuromuscular block will be monitored at their arrival to the Post-Anesthesia Care Unit to assess the presence of residual neuromuscular block.

Study summary

The use of neuromuscular blockers (NMB) is essential to optimize surgical conditions, ensure patient immobility during the intervention and prevent complications derived from involuntary movements. Intraoperative monitoring of neuromuscular relaxation allows the depth of neuromuscular blockade to be accurately evaluated, guaranteeing ideal conditions for the surgical team. Residual neuromuscular blockade (RNMB) is the persistence of muscle paralysis after the administration of NMB during a surgical intervention. The appearance of RNMB poses substantial challenges in the postoperative period, as it has negative repercussions for the safety and well-being of the patient.

Eligibility

Primary outcome measure(s)

• Residual Neuromuscular Block — 5 minutes postoperatively
  Train-Of-Four ratio at arrival to the Post-Anesthetic Care Unit
• Residual Neuromuscular Block — 8 minutes postoperatively
  Train-Of-Four ratio 3 minutes after the arrival to the Post-Anesthetic Care Unit

Trial sites (2)

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