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Clinical Trials in Spain / NCT05615051
Active, not recruiting Not applicable

Influence of Implant Surface Decontamination on the Reconstructive Outcomes of Peri-implantitis

NCT05615051 · tracked via the Priya Life Science Spain tracker
Sponsor
Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Phase
Not applicable
Started
2022-01-01
Last updated
2026-06-08

Condition(s) studied

Peri-Implantitis

Investigational drug(s) / intervention(s)

Surface decontamination procedure aiming at reconstructive therapy

Surface decontamination procedure aiming at reconstructive therapy: Surface decontamination of infected implants followed by reconstructive therapy to manage peri-implantitis

Study summary

Two groups are aimed at being investigated in three centers (CICOM, Clinica Branemark and Clinica Joan Pi)

* Test group: Group electrolytic approach (EA): Mechanical detoxification using curettes + NiTi brushes + EA (GalvoSurge) during 2 minutes
* Control group: Group hydrogen peroxide (HP): Mechanical detoxification using curettes + NiTi brushes + hydrogen peroxide 5% for 2 minutes soaked in a gauze Patients´ group selection will be randomly allocated. For patients whom their personal clinical record # ends in a number from 0 to 4 will be included in the test group, while for patients whom their personal clinical record # ends from 5-9 will be included in the control group.

The infra-osseous component will be regenerated using xenograft (Creos, NB) + autogenous bone in a ratio 1:1 harvested from the adjacent area. A resorbable membrane (Creos, NB) will be placed to compartmentalize the infra-osseous component following a poncho-like approach.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
Accepted
Inclusion: * Screw-retained or cement-retained fixed or removable implant-supported prosthesis for a minimum of 36 months. * All patients in age of 18 to 80 * non-smokers * no presence of systemic disease or medication known to alter bone metabolism * partial or complete edentulous patients that have no active periodontal disease. Exclusion criteria: * pregnancy or lactation * history of or current smokers * uncontrolled medical conditions, * lacking keratinized mucosa (≤2mm) on the lingual or buccal implant sites, * advanced(A) peri-implantitis (\>50% of the implant length).

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Clinica CICOM Badajoz Spain

More Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain trials in Spain

Occurrence of Peri-Implant Complications: A Multifactorial Cross-Sectional Study Recruiting

Other trials for the same condition

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Non-surgical Treatment of Peri-implant Pockets With H42 Recruiting
The Adjunctive Effect of a Titanium Brush in the Non-Surgical Treatment of Peri-Implantitis Recruiting
Polynucleotide and Hyaluronic Acid-based Gel as Adjunctive Therapy to Non- Surgical Treatment of Intraosseous Peri-implant Defect. A Randomized Clinical Trial Starting soon
Non-Surgical Treatment of Peri-implantitis with Systemic Azithromycin or Placebo Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05615051 on ClinicalTrials.gov ↗ ← All trials in Spain