Exercise training: Exercise program for 24 weeks (with neo-adjuvant treatment), with two sessions per week including both moderate-to-intense aerobic and resistance training. The intensity of each type of exercise will range between 65% and 100% of the maximum score in the Rated Perceived Exertion (RPE) scale.
Control: Yoga + educational program
Study summary
To assess in women with triple-negative breast cancer receiving neo-adjuvant chemotherapy the effects of an intense physical exercise program (intervention group) on physical capacity, compared with a control group not meeting the minimum exercise recommendations of the World Health Organization (WHO).
Eligibility
Sex
FEMALE
Min age
25 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria:
* Diagnosed with breast carcinoma in the 'Hospital Universitario Quirónsalud de Pozuelo' (Madrid, Spain) and following neoadjuvant therapy in the aforementioned center.
* Must have triple negative breast cancer (i.e., negative for estrogen receptors, progesterone receptors, and excess HER2 protein) of size \> or equal to 15 mm
Exclusion Criteria:
* Not meeting all of the above.
Primary outcome measure(s)
Cardiorespiratory fitness — Change from baseline to end of intervention (i.e., after 24 weeks) peak rate of oxygen consumption (ml/kg/min) reached during a graded treadmill exercise test until exhaustion
muscle dynamic strength — Change from baseline to end of intervention (i.e., after 24 weeks) Time (seconds) to perform the sit-to-stand (STS) test (five consecutive repetitions of sitting down and uprising from a chair)
handgrip strength — Change from baseline to end of intervention (i.e., after 24 weeks) handgrip strength measured using a dynamometer and scores recorded in kilograms (to the nearest 0.1 kg)
Trial sites (2)
Facility
City
Region
Status
Hospital Universitario Quirónsalud de Pozuelo (HUQP)
Madrid
Spain
Recruiting
Lgcortijo@Gmail.Com
Madrid
Spain
Recruiting
More Universidad Europea de Madrid trials in Spain
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.
