The Akershus Study of Ischemic Stroke and Thrombolysis -1

Condition(s) studied

Study summary

This observational study comprises consecutively patients with cerebrovascular diseases admitted to the Stroke Unit at Akershus University Hospital in Norway. Akershus University Hospital is the largest emergency care hospital in Norway and has a catchment area covering a population of 550.000, which is approximately 10 % of the Norwegian population and reasonably representative according to data from Statistics Norway. The hospital is public and serving both as a primary hospital and a university hospital. Due to the Norwegian, national, all-covering health-insurance, all patients enter the hospital and are considered for further in-patient care on the same conditions. The hospital has a stroke unit classified as a comprehensive stroke center according to European Stroke Organisation standards. Acute stroke management follows national and international guidelines. Overall, the ASIST-1 study will investigate management, outcome and prognosis of stroke and stroke care pathways and later follow up in primary care using several approaches combining existing clinical data from a representative population with different Norwegian health registries. Parts of the study are retrospective with prospective follow-up by health registries and parts of the study are prospective.

Eligibility

Primary outcome measure(s)

• Large vessel occlusion in a representative Norwegian population — Baseline 2015-2017
  Incidence of large vessel occlusion 2015-2017
• Functional status — 3 months
  modified Rankin Scale (mRS) 0-6 (0 normal, 6 dead) for all groups
• Functional status — Index discharge from hospital, usually up to 1 month
  modified Rankin Scale (mRS) 0-6 (0 normal, 6 dead) for all groups
• Mortality — In-hospital, usually up to 1 month
  Number dead vs total number of cases all groups
• Mortality — 3 months
  Number dead vs total number of cases all groups
• Mortality — 12 months
  Number dead vs total number of cases all groups
• Mortality — 24 months
  Number dead vs total number of cases all groups
• Mortality — 5 years
  Number dead vs total number of cases all groups
• Diagnostic precision of different published clinical screening scales of stroke and large vessel occlusion — Baseline 2015-2017
  Diagnostic precision, accuracy and validity of clinical screening scales

Trial sites (1)

More University Hospital, Akershus trials in Norway

Other trials for the same condition