GUIDed Growth of the Proximal Femur to Prevent Further Hip MigrAtion in CErebral Palsy Patients

Condition(s) studied

Investigational drug(s) / intervention(s)

Temporary Medial Hemi-epiphysiodesis of the proximal femur: Temporary Medial Hemi-epiphysiodesis of the proximal femur

Study summary

In recent literature, the potential of guided growth of the proximal femur to modify hip growth in patients with cerebral palsy has been shown. Using medial hemi-epiphysiodesis of the proximal femur (TMH-PF) morphology of hips at risk of symptomatic (sub)luxation in cerebral palsy (CP) can be changed, aiming to reduce further hip migration and the need for more invasive surgical treatment modalities. Further research is necessary to assess if the results of TMH-PF in combination with adductor tenotomies are significantly better than the results of the current standard of care; adductor tenotomies alone.

The investigators objective is to determine whether guided growth of the proximal femur decreases the risk of further hip migration and need for further surgery in cerebral palsy patients.

Eligibility

Primary outcome measure(s)

• Treatment failure — from enrollment to the end of study (8 years)
  The Primary study outcome is treatment failure, defined as: * Need for secondary bony hip surgery to the affected hip or progression to hip migration \> 50% at 5-year follow-up . An indication for secondary bony surgery will be defined as; * Migration percentage \> 50% at a minimum of 1 year after surgery, OR * An increased migration \> 10% in 1 year during follow-up * Increase in Acetabular index to \> 30 degrees or an increase of more than 5 degrees during follow-up

Trial sites (5)

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