FDG PET/CT: Besides the standard care FDG PET/CT examination, subjects receive a dynamic whole body PET/CT examination.
Study summary
The goal of this study is to evaluate the use of new method to quantify the amount of sugar a tumor consumes using PET/CT. The main questions it aims to answer are:
* Is the new quantification method superior with respect to the method currently used in the clinic?
* Does the new quantification method provide accurate assessment of the sugar consumption of tumours?
Participants who will undergo a standard care FDG PET/CT scan will in additional receive a dynamic PET/CT scan prior to the standard care scan. In addition blood samples will be drawn at three time points during the examination.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Patients who receive an 18F FDG PET/CT scan as part of standard care
* Be competent and be 18 years of age or older
Exclusion Criteria:
* Diabetes (fasted blood glucose \> 7 mmol/L)
* Not fasted \> 4 hours
* Physical exercise within 24 hours
* Earlier treatment for carcinoma with radio/chemo-therapy
* Active inflammation (fever \> 38 degrees, CRP \> 5)
* Any condition or medical indication (such as claustrophobia) that indicates that the patient will not be able to lie still for the duration of the dynamic PET/CT examination
* Pregnant or breast feeding
Primary outcome measure(s)
Superiority of the FUR compared to the SUV — Time of PET examination The correlation between the fractional uptake rate (FUR) and the metabolic glucose consumption (Km) will be compared to the correlation between the standardized uptake value (SUV) and Km
Trial sites (1)
Facility
City
Region
Status
Academisch ziekenhuis Maastricht
Maastricht
Limburg
Recruiting
More Academisch Ziekenhuis Maastricht trials in the Netherlands
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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