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Clinical Trials in Mexico / NCT04648228
Active, not recruiting Not applicable

Pain and Opioids: Integrated Treatment In Veterans

NCT04648228 · tracked via the Priya Life Science Mexico tracker
Sponsor
University of New Mexico
Phase
Not applicable
Started
2021-07-01
Last updated
2025-12-22

Condition(s) studied

Chronic PainOpioid-use DisorderOpioids; Harmful Use

Investigational drug(s) / intervention(s)

ACT+MBRPEducation control

ACT+MBRP: Intervention is behavioral treatment group that combines Acceptance and Commitment Therapy (ACT) with Mindfulness-Based Relapse Prevention. The group focuses on living with long-term pain, ways to complete daily living activities when you experience pain, coping with opioid and other drug cravings, and training in mindfulness practices.

Education control: Education control is behavioral treatment group that combines pain patient education with opioid and other drug education. The group focuses on experiences of long-term pain, instructions on how to function with this pain, and facts about opioids and other drugs.

Study summary

This trial will recruit veterans with chronic pain (N = 160) who are prescribed buprenorphine for the treatment of opioid use disorder (OUD). We seek to: (1) examine the efficacy of an integrated treatment to reduce pain interference (Acceptance and Commitment Therapy and Mindfulness-Based Relapse Prevention \[ACT + MBRP\]) compared to an education control (EC) consisting of a protocol-based series of education sessions concerning chronic pain, opioids, and buprenorphine use and (2) examine how theoretically-relevant treatment mechanisms of pain acceptance, engagement in values-based action, and opioid craving are related to treatment outcomes. Interventions will be delivered via the VA Video Connect telehealth modality.

Eligibility

Sex
ALL
Min age
21 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria: 1. Stabilized on a dose of buprenorphine for a period of at least 1 month and less than six months. Buprenorphine stabilization will be defined as a consistent dose for at least 30 consecutive days. 2. Willing to comply with all study procedures and be available for the duration of the study 3. Male or female, aged 21 to 75 years. 4. Enrolled as a patient in one of the participating VA Co-Occurring Disorders clinics. 5. Presence of chronic pain for \> 6 months in duration. Exclusion Criteria: 1. Current or past diagnosis of schizophrenia, delusional disorder, psychotic or dissociative disorders. 2. Unable to read English. 3. Have a substance use disorder requiring a higher level of care than outpatient treatment (e.g., severe alcohol use disorder requiring inpatient detoxification).

Primary outcome measure(s)

Trial sites (4)

FacilityCityRegionStatus
San Francisco VA Health Care System San Francisco California
New Mexico VA Healthcare System Albuquerque New Mexico
University of New Mexico Albuquerque New Mexico
Puget Sound VA Healthcare System Tacoma Washington

More University of New Mexico trials in Mexico

Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-Stroke Recruiting
Catholic Health Initiatives (CHI) St. Joseph's Children Home Visiting Longitudinal Study Active, not recruiting
PREPARE: Perioperative REhabilitation Around Vaginal Prolapse RepAir Surgery for Recovery Enhancement Recruiting
Opioid Adherence and Support Through Innovative Texting Strategies Recruiting
Healing Opioid Misuse and Pain Through Engagement (HOPE) Trial Active, not recruiting

Other trials for the same condition

Opioid Adherence and Support Through Innovative Texting Strategies Recruiting
Healing Opioid Misuse and Pain Through Engagement (HOPE) Trial Active, not recruiting
Mindfulness Texting for Medication Adherence and Chronic Pain Management Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04648228 on ClinicalTrials.gov ↗ ← All trials in Mexico