Evaluation of adherence, persistence and efficacy of treatment with Inclisiran in a real-life Italian population
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Patients under Inclisiran treatment
Exclusion Criteria:
* Age \< 18 years o \> 80 years
* Patients who refuse to participate and to sign informed consent
Primary outcome measure(s)
Description of adherence to treatment with Inclisiran in a real-life Italian population — at 3 months and every 6 months thereafter Adherence will be assessed in terms of Medical Possession Ratio (MPR) which is defined as the ratio between the treatment units dispensed during the treatment period and the duration of the treatment period itself.
Description of persistence to treatment with Inclisiran in a real-life Italian population — at 3 months and every 6 months thereafter Persistence will be assessed in terms of therapeutic continuity from the start of treatment to enrollment.
Description of efficacy of treatment with Inclisiran in a real-life Italian population — at 3 months and every 6 months thereafter Efficacy of treatment will be evaluated as a change in the LDL (deltaLDL) value from the start of treatment (percentage and absolute value). The deltaLDL will be calculated as an overall (mean and median value), by type of prevention (primary and secondary), by type of basic therapy, by demographic variables (age, sex, geographic origin, basal LDL levels) and by type of prescriber (hospital or territorial).
Trial sites (1)
Facility
City
Region
Status
Federico II University of Naples, Department of Advanced Biomedical Sciences
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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