The goal of this feasibility study is to evaluate a new sample preparator called See.d.
After blood processing the instrument will produce a set of slides and a tube of plasma. These outputs could be used in further analysis in liquid biopsy applications.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* Participants are willing and able to give and sign a written informed consent
* Aged 18 or above
Exclusion Criteria:
* Ongoing infections requiring antibiotic or antiviral treatment
* Known hemostasis/coagulation disorder
* Known Pregnancy
Primary outcome measure(s)
SBS slides stability — 1 day (at the blood draw) Evaluation of the area of adhered cell nuclei on SBS slides
Reagents stability — 1 day (at the blood draw) Evaluation of total adhered cell count on SBS slides
cfDNA quality control — 1 day (at the blood draw) Evaluation of the ratio between cfDNA and genomic contaminant DNA
Feasibility of staining on slides produced by See.d — 1 day (at the blood draw) Qualitative assessment of staining positivity
Feasibility of using See.d SBS slides for subsequent analysis — 1 day (at the blood draw) Recovery of mock-Circulating Tumor Cells (CTCs)
Feasibility of using See.d plasma for subsequent analysis — 1 day (at the blood draw) Recovery of spiked reference DNA
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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