Atrial Fibrillation Radiofrequency Ablation Only: Comparison between two mapping catheters, Optrell vs Octaray, in the same patient
Study summary
This prospective, single-center observational study aims to compare the clinical performance, workflow efficiency, and electrophysiological metrics of two commercially available, high-density multielectrode mapping catheters (Octaray and Optrell) in patients undergoing catheter ablation for complex atrial arrhythmias.
The primary focus is to determine if the real-time vector propagation capabilities of the Optrell catheter combined with V8 software can accurately confirm conduction block across linear ablation lesions without the need for full-chamber activation remapping, which is the current standard of care. A secondary focus will pair-compare the bipolar voltage amplitude distributions recorded by both catheters, given their differing electrode sizes and spacing.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* • Age ≥18 years.
* • Documented persistent atrial fibrillation and/or atrial flutter.
* • Undergoing a clinically indicated first-time (de novo) or redo catheter ablation where linear ablation lesion sets (e.g., posterior wall, roof line, lateral mitral line, CTI) are planned or anticipated.
* • Ability to provide written informed consent.
Exclusion Criteria:
* • Paroxysmal or persistent AF where only standard PVI is planned.
* • Mechanical mitral valve.
* • Presence of intracardiac thrombus or contraindication to systemic anticoagulation.
* • Any medical condition or anatomical contraindication that, in the investigator's judgment, precludes safe participation.
* • Pregnant women.
Primary outcome measure(s)
Concordance — During ablation procedure Percentage of agreement (presence vs. absence of bidirectional block) between the Optrell real-time vector assessment and standard activation remapping on a per-line basis.
Workflow Efficiency — During ablation procedure Difference in time (in minutes) required to confirm conduction block status using the Optrell vector method versus full activation mapping.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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